SCOPe 2.03: Domain d4fxyp_: 4fxy P:

Lineage for d4fxyp_ (4fxy P:)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.92: Zincin-like [55485] (2 superfamilies)
   contains mixed beta sheet with connection over free side of the sheet

4. Superfamily d.92.1: Metalloproteases ("zincins"), catalytic domain [55486] (18 families)

5. Family d.92.1.5: Neurolysin-like [55505] (5 proteins)
   combines M2, M3 and M32 families of metalloproteases
   the N-terminal half of the structure is multihelical; the C-terminal half contains the thermolysin-like catalytic domain

6. Protein automated matches [190340] (3 species)
   not a true protein

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [187944] (2 PDB entries)

8. Domain d4fxyp_: 4fxy P: [234434]
   automated match to d4fxyq_
   complexed with 0w2, zn

Details for d4fxyp_

PDB Entry: 4fxy, 2.8 Å

PDB Description: crystal structure of rat neurolysin with bound pyrazolidin inhibitor

PDB Compounds: (P:) Neurolysin, mitochondrial

SCOPe Domain Sequences for d4fxyp_:

Sequence; same for both SEQRES and ATOM records:

>d4fxyp_ d.92.1.5 (P:) automated matches {Norway rat (Rattus norvegicus) [TaxId: 10116]}
ssytaagrnvlrwdlspeqiktrteqliaqtkqvydtvgtialkevtyenclqvladiev
tyivertmldfpqhvssdrevraasteadkklsrfdiemsmredvfqrivhlqetcdlek
ikpearryleksikmgkrnglhlseairneiksmkkrmselcidfnknlneddtslvfsk
aelgalpddfidslektdedkykvtlkyphyfpvmkkccvpetrrkmemafhtrckqent
ailqqllplraqvakllgynthadfvlelntakstsrvaaflddlsqklkplgeaerefi
lslkkkeceergfeydgkinawdlhyymtqteelkysvdqeslkeyfpievvtegllsiy
qellglsfeqvpdahvwnksvslytvkdkatgevlgqfyldlypregkynhaacfglqpg
cllpdgsrmmsvaalvvnfsqpvagrpsllrhdevrtyfhefghvmhqicaqtdfarfsg
tnvetdfvevpsqmlenwvwdvdslrklskhykdghpitdelleklvasrlvntglltlr
qivlskvdqslhtnatldaaseyakycteilgvaatpgtnmpatfghlaggydgqyygyl
wsevfsmdmfhscfkkegimnpevgmkyrnlilkpggsldgmdmlqnflqrepnqkaflm
srgl

Timeline for d4fxyp_:

• d4fxyp_ is new in SCOPe 2.03-stable
  
• d4fxyp_ appears in SCOPe 2.04
  
• d4fxyp_ appears in the current release, SCOPe 2.08