SCOPe 2.08: Domain d4e4na1: 4e4n A:854-1154

Lineage for d4e4na1 (4e4n A:854-1154)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (37 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1476 PDB entries)

8. Domain d4e4na1: 4e4n A:854-1154 [234360]
   Other proteins in same PDB: d4e4na2
   automated match to d4ehza_
   complexed with 0nl

Details for d4e4na1

PDB Entry: 4e4n, 1.9 Å

PDB Description: JAK1 kinase (JH1 domain) in complex with compound 49

PDB Compounds: (A:) Tyrosine-protein kinase JAK1

SCOPe Domain Sequences for d4e4na1:

Sequence, based on SEQRES records:

>d4e4na1 d.144.1.0 (A:854-1154) automated matches {Human (Homo sapiens) [TaxId: 9606]}
divsekkpatevdpthfekrflkrirdlgeghfgkvelcrydpegdntgeqvavkslkpe
sggnhiadlkkeieilrnlyhenivkykgictedggngiklimeflpsgslkeylpknkn
kinlkqqlkyavqickgmdylgsrqyvhrdlaarnvlvesehqvkigdfgltkaietdke
yytvkddrdspvfwyapeclmqskfyiasdvwsfgvtlhelltycdsdsspmalflkmig
pthgqmtvtrlvntlkegkrlpcppncpdevyqlmrkcwefqpsnrtsfqnliegfeall
k

Sequence, based on observed residues (ATOM records):

>d4e4na1 d.144.1.0 (A:854-1154) automated matches {Human (Homo sapiens) [TaxId: 9606]}
divsekkpatevdpthfekrflkrirdlgeghfgkvelcrydpegdntgeqvavkslkph
iadlkkeieilrnlyhenivkykgictegiklimeflpsgslkeylpknknkinlkqqlk
yavqickgmdylgsrqyvhrdlaarnvlvesehqvkigdfgltkaietdkeyytvkddrd
spvfwyapeclmqskfyiasdvwsfgvtlhelltycdsdsspmalflkmigpthgqmtvt
rlvntlkegkrlpcppncpdevyqlmrkcwefqpsnrtsfqnliegfeallk

Timeline for d4e4na1:

• d4e4na1 first appeared in SCOPe 2.03, called d4e4na_
  
• d4e4na1 appears in SCOPe 2.07