SCOPe 2.03: Domain d4bo0c_: 4bo0 C:

Lineage for d4bo0c_ (4bo0 C:)

1. Root: SCOPe 2.03

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.0: automated matches [191313] (1 protein)
   not a true family

6. Protein automated matches [190069] (159 species)
   not a true protein

7. Species Pseudomonas aeruginosa [TaxId:208964] [196452] (24 PDB entries)

8. Domain d4bo0c_: 4bo0 C: [234236]
   automated match to d4afna_
   complexed with fxe, ni

Details for d4bo0c_

PDB Entry: 4bo0, 2.4 Å

PDB Description: Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with 1-(4-methoxy-1- methylindazol-3-yl)-3-(2-methoxyphenyl)urea at 2.4A resolution

PDB Compounds: (C:) 3-oxoacyl-[acyl-carrier-protein] reductase FabG

SCOPe Domain Sequences for d4bo0c_:

Sequence, based on SEQRES records:

>d4bo0c_ c.2.1.0 (C:) automated matches {Pseudomonas aeruginosa [TaxId: 208964]}
hhhhhssgvdlgtenlyfqsmslqgkvalvtgasrgigqaialelgrlgavvigtatsas
gaekiaetlkangvegaglvldvssdesvaatlehiqqhlgqplivvnnagitrdnllvr
mkddewfdvvntnlnslyrlskavlrgmtkarwgriinigsvvgamgnagqtnyaaakag
legftralarevgsraitvnavapgfidtdmtrelpeaqreallgqiplgrlgqaeeiak
vvgflasdgaayvtgatvpvnggmyms

Sequence, based on observed residues (ATOM records):

>d4bo0c_ c.2.1.0 (C:) automated matches {Pseudomonas aeruginosa [TaxId: 208964]}
hhhhhsslyfqsmslqgkvalvtgasrgigqaialelgrlgavvigtatsasgaekiaet
lkangvegaglvldvssdesvaatlehiqqhlgqplivvnnagitrdewfdvvntnlnsl
yrlskavlrgmtkarwgriinigsvvgqtnyaaakaglegftralarevgsraitvnava
pgfidtdmtrelpeaqreallgqiplgrlgqaeeiakvvgflasdgaayvtgatvpvngg
myms

Timeline for d4bo0c_:

• d4bo0c_ is new in SCOPe 2.03-stable
  
• d4bo0c_ appears in SCOPe 2.04
  
• d4bo0c_ appears in the current release, SCOPe 2.08, called d4bo0c1