SCOPe 2.06: Domain d4bnxb1: 4bnx B:1-246

Lineage for d4bnxb1 (4bnx B:1-246)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.2: NAD(P)-binding Rossmann-fold domains [51734] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 6 strands, order 321456
   The nucleotide-binding modes of this and the next two folds/superfamilies are similar

4. Superfamily c.2.1: NAD(P)-binding Rossmann-fold domains [51735] (13 families)

5. Family c.2.1.0: automated matches [191313] (1 protein)
   not a true family

6. Protein automated matches [190069] (239 species)
   not a true protein

7. Species Pseudomonas aeruginosa, PA01 [TaxId:208964] [196452] (27 PDB entries)

8. Domain d4bnxb1: 4bnx B:1-246 [234220]
   Other proteins in same PDB: d4bnxa2, d4bnxb2, d4bnxc2, d4bnxd2
   automated match to d4afna_
   complexed with o74

Details for d4bnxb1

PDB Entry: 4bnx, 2.3 Å

PDB Description: crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with 6-(4-(2-chloroanilino)- 1h-quinazolin-2-ylidene)cyclohexa-2, 4-dien-1-one at 2.3a resolution

PDB Compounds: (B:) 3-oxoacyl-[acyl-carrier-protein] reductase FabG

SCOPe Domain Sequences for d4bnxb1:

Sequence, based on SEQRES records:

>d4bnxb1 c.2.1.0 (B:1-246) automated matches {Pseudomonas aeruginosa, PA01 [TaxId: 208964]}
mslqgkvalvtgasrgigqaialelgrlgavvigtatsasgaekiaetlkangvegaglv
ldvssdesvaatlehiqqhlgqplivvnnagitrdnllvrmkddewfdvvntnlnslyrl
skavlrgmtkarwgriinigsvvgamgnagqtnyaaakaglegftralarevgsraitvn
avapgfidtdmtrelpeaqreallgqiplgrlgqaeeiakvvgflasdgaayvtgatvpv
nggmym

Sequence, based on observed residues (ATOM records):

>d4bnxb1 c.2.1.0 (B:1-246) automated matches {Pseudomonas aeruginosa, PA01 [TaxId: 208964]}
mslqgkvalvtgasrgigqaialelgrlgavvigtatsasgaekiaetlkangvegaglv
ldvssdesvaatlehiqqhlgqplivvnnamkddewfdvvntnlnslyrlskavlrgmtk
arwgriinigsvvgamgnagqtnyaaakaglegftralarevgsraitvnavapgfidtd
mtrelpeaqreallgqiplgrlgqaeeiakvvgflasdgaayvtgatvpvnggmym

Timeline for d4bnxb1:

• d4bnxb1 first appeared in SCOPe 2.03, called d4bnxb_
  
• d4bnxb1 was called d4bnxb_ in SCOPe 2.05
  
• d4bnxb1 appears in SCOPe 2.07
  
• d4bnxb1 appears in the current release, SCOPe 2.08