Lineage for d4afjb_ (4afj B:)

  1. Root: SCOPe 2.04
  2. 1631855Class d: Alpha and beta proteins (a+b) [53931] (380 folds)
  3. 1671717Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1671718Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1671838Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1673984Protein automated matches [190091] (13 species)
    not a true protein
  7. 1674055Species Human (Homo sapiens) [TaxId:9606] [188447] (490 PDB entries)
  8. 1674192Domain d4afjb_: 4afj B: [234062]
    automated match to d4afja_
    complexed with gol, sjj, so4

Details for d4afjb_

PDB Entry: 4afj (more details), 1.98 Å

PDB Description: 5-aryl-4-carboxamide-1,3-oxazoles: potent and selective gsk-3 inhibitors
PDB Compounds: (B:) Glycogen synthase kinase-3 beta

SCOPe Domain Sequences for d4afjb_:

Sequence, based on SEQRES records: (download)

>d4afjb_ d.144.1.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gskvttvvatpgqgpdrpqevsytdtkvigngsfgvvyqaklcdsgelvaikkvlqdkrf
knrelqimrkldhcnivrlryffyssgekkdevylnlvldyvpetvyrvarhysrakqtl
pviyvklymyqlfrslayihsfgichrdikpqnllldpdtavlklcdfgsakqlvrgepn
vsyicsryyrapelifgatdytssidvwsagcvlaelllgqpifpgdsgvdqlveiikvl
gtptreqiremnpnytefkfpqikahpwtkvfrprtppeaialcsrlleytptarltple
acahsffdelrdpnvklpngrdtpalfnfttqelssnpplatilipphari

Sequence, based on observed residues (ATOM records): (download)

>d4afjb_ d.144.1.7 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gskvttvvatpgqgpdrpqevsytdtkvigngsfgvvyqaklcdsgelvaikkvlqknre
lqimrkldhcnivrlryffyssgekkdevylnlvldyvpetvyrvarhysrakqtlpviy
vklymyqlfrslayihsfgichrdikpqnllldpdtavlklcdfgsakqlvrgepnvsyi
csryyrapelifgatdytssidvwsagcvlaelllgqpifpgdsgvdqlveiikvlgtpt
reqiremnpnytefkfpqikahpwtkvfrprtppeaialcsrlleytptarltpleacah
sffdelrdpnvklpngrdtpalfnfttqelssnpplatilipphari

SCOPe Domain Coordinates for d4afjb_:

Click to download the PDB-style file with coordinates for d4afjb_.
(The format of our PDB-style files is described here.)

Timeline for d4afjb_: