SCOPe 2.08: Domain d4aela1: 4ael A:449-767

Lineage for d4aela1 (4ael A:449-767)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
   multihelical; consists of two different alpha-helical bundles

4. Superfamily a.211.1: HD-domain/PDEase-like [109604] (9 families)

5. Family a.211.1.0: automated matches [191566] (1 protein)
   not a true family

6. Protein automated matches [190983] (12 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188676] (139 PDB entries)

8. Domain d4aela1: 4ael A:449-767 [234060]
   Other proteins in same PDB: d4aela2, d4aelb2
   automated match to d3wi2a_
   complexed with 4hn, mg, zn

Details for d4aela1

PDB Entry: 4ael, 2.2 Å

PDB Description: PDE10A in complex with the inhibitor AZ5

PDB Compounds: (A:) camp and camp-inhibited cgmp 3', 5'-cyclic phosphodiesterase 10a

SCOPe Domain Sequences for d4aela1:

Sequence; same for both SEQRES and ATOM records:

>d4aela1 a.211.1.0 (A:449-767) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sictseewqglmqftlpvrlckeielfhfdigpfenmwpgifvymvhrscgtscfelekl
crfimsvkknyrrvpyhnwkhavtvahcmyailqnnhtlftdlerkglliaclchdldhr
gfsnsylqkfdhplaalyststmeqhhfsqtvsilqleghnifstlssseyeqvleiirk
aiiatdlalyfgnrkqleemyqtgslnlnnqshrdrviglmmtacdlcsvtklwpvtklt
andiyaefwaegdemkklgiqpipmmdrdkkdevpqgqlgfynavaipcyttltqilppt
epllkacrdnlsqwekvir

Timeline for d4aela1:

• d4aela1 first appeared in SCOPe 2.03, called d4aela_
  
• d4aela1 appears in SCOPe 2.07