SCOPe 2.05: Domain d3zh8c_: 3zh8 C:

Lineage for d3zh8c_ (3zh8 C:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (21 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (615 PDB entries)

8. Domain d3zh8c_: 3zh8 C: [233988]
   automated match to d3zh8b_
   complexed with c58, cl, edo, iod

Details for d3zh8c_

PDB Entry: 3zh8, 2.74 Å

PDB Description: a novel small molecule apkc inhibitor

PDB Compounds: (C:) Protein kinase C iota type

SCOPe Domain Sequences for d3zh8c_:

Sequence, based on SEQRES records:

>d3zh8c_ d.144.1.0 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
slglqdfdllrvigrgsyakvllvrlkktdriyamkvvkkelvnddedidwvqtekhvfe
qasnhpflvglhscfqtesrlffvieyvnggdlmfhmqrqrklpeeharfysaeislaln
ylhergiiyrdlkldnvlldseghikltdygmckeglrpgdttstfcgtpnyiapeilrg
edygfsvdwwalgvlmfemmagrspfdivgssdnpdqntedylfqvilekqiriprslsv
kaasvlksflnkdpkerlgchpqtgfadiqghpffrnvdwdmmeqkqvvppfkpnisgef
gldnfdsqftnepvqltpddddivrkidqsefegfeyinpl

Sequence, based on observed residues (ATOM records):

>d3zh8c_ d.144.1.0 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
slglqdfdllrvigrgsyakvllvrlkktdriyamkvvkkelvnddedidwvqtekhvfe
qasnhpflvglhscfqtesrlffvieyvnggdlmfhmqrqrklpeeharfysaeislaln
ylhergiiyrdlkldnvlldseghikltdygmckeglrpgdttstfcgtpnyiapeilrg
edygfsvdwwalgvlmfemmagrspfdivntedylfqvilekqiriprslsvkaasvlks
flnkdpkerlgchpqtgfadiqghpffrnvdwdmmeqkqvvppfkpnqltpddddivrki
dqsefegfeyinpl

Timeline for d3zh8c_:

• d3zh8c_ first appeared in SCOPe 2.03
  
• d3zh8c_ appears in SCOPe 2.04
  
• d3zh8c_ appears in SCOPe 2.06
  
• d3zh8c_ appears in the current release, SCOPe 2.08