SCOPe 2.03: Domain d3wixb_: 3wix B:

Lineage for d3wixb_ (3wix B:)

1. Root: SCOPe 2.03

2. Class f: Membrane and cell surface proteins and peptides [56835] (57 folds)

3. Fold f.1: Toxins' membrane translocation domains [56836] (5 superfamilies)
   multi-helical domains of various folds which is thought to unfold in the membrane

4. Superfamily f.1.4: Bcl-2 inhibitors of programmed cell death [56854] (2 families)
   PROVISIONAL CLASSIFICATION, based on structural similarity to the diphtheria toxin domain

5. Family f.1.4.1: Bcl-2 inhibitors of programmed cell death [56855] (11 proteins)
   Pfam PF00452

6. Protein automated matches [190236] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188722] (29 PDB entries)

8. Domain d3wixb_: 3wix B: [233963]
   automated match to d3wiye_
   complexed with lc3

Details for d3wixb_

PDB Entry: 3wix, 1.9 Å

PDB Description: Crystal structure of Mcl-1 in complex with compound 4

PDB Compounds: (B:) Induced myeloid leukemia cell differentiation protein Mcl-1

SCOPe Domain Sequences for d3wixb_:

Sequence; same for both SEQRES and ATOM records:

>d3wixb_ f.1.4.1 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
delyrqsleiisrylreqatgakdtkpmgrsgatsrkaletlrrvgdgvqrnhetafqgm
lrkldikneddvkslsrvmihvfsdgvtnwgrivtlisfgafvakhlktinqesciepla
esitdvlvrtkrdwlvkqrgwdgfveffhv

Timeline for d3wixb_:

• d3wixb_ is new in SCOPe 2.03-stable
  
• d3wixb_ appears in SCOPe 2.04
  
• d3wixb_ appears in the current release, SCOPe 2.08