Lineage for d3uuoa_ (3uuo A:)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2342123Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
    multihelical; consists of two different alpha-helical bundles
  4. 2342124Superfamily a.211.1: HD-domain/PDEase-like [109604] (6 families) (S)
  5. 2342564Family a.211.1.0: automated matches [191566] (1 protein)
    not a true family
  6. 2342565Protein automated matches [190983] (9 species)
    not a true protein
  7. 2342579Species Human (Homo sapiens) [TaxId:9606] [188676] (127 PDB entries)
  8. 2342653Domain d3uuoa_: 3uuo A: [233803]
    automated match to d3wi2a_
    complexed with 0cv, mg, po4, zn

Details for d3uuoa_

PDB Entry: 3uuo (more details), 2.11 Å

PDB Description: The discovery of potent, selectivity, and orally bioavailable pyrozoloquinolines as PDE10 inhibitors for the treatment of Schizophrenia
PDB Compounds: (A:) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

SCOPe Domain Sequences for d3uuoa_:

Sequence; same for both SEQRES and ATOM records: (download)

>d3uuoa_ a.211.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d3uuoa_:

Click to download the PDB-style file with coordinates for d3uuoa_.
(The format of our PDB-style files is described here.)

Timeline for d3uuoa_: