SCOPe 2.07: Domain d3sn7b1: 3sn7 B:439-759

Lineage for d3sn7b1 (3sn7 B:439-759)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
   multihelical; consists of two different alpha-helical bundles

4. Superfamily a.211.1: HD-domain/PDEase-like [109604] (6 families)

5. Family a.211.1.0: automated matches [191566] (1 protein)
   not a true family

6. Protein automated matches [190983] (10 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188676] (136 PDB entries)

8. Domain d3sn7b1: 3sn7 B:439-759 [233565]
   Other proteins in same PDB: d3sn7a2, d3sn7b2
   automated match to d3wi2a_
   complexed with 540, cl, mg, zn

Details for d3sn7b1

PDB Entry: 3sn7, 1.82 Å

PDB Description: highly potent, selective, and orally active phosphodiestarase 10a inhibitors

PDB Compounds: (B:) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

SCOPe Domain Sequences for d3sn7b1:

Sequence, based on SEQRES records:

>d3sn7b1 a.211.1.0 (B:439-759) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sictseewqglmqftlpvrlckeielfhfdigpfenmwpgifvymvhrscgtscfelekl
crfimsvkknyrrvpyhnwkhavtvahcmyailqnnhtlftdlerkglliaclchdldhr
gfsnsylqkfdhplaalyststmeqhhfsqtvsilqleghnifstlssseyeqvleiirk
aiiatdlalyfgnrkqleemyqtgslnlnnqshrdrviglmmtacdlcsvtklwpvtklt
andiyaefwaegdemkklgiqpipmmdrdkkdevpqgqlgfynavaipcyttltqilppt
epllkacrdnlsqwekvirge

Sequence, based on observed residues (ATOM records):

>d3sn7b1 a.211.1.0 (B:439-759) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sictseewqglmqftlpvrlckeielfhfdigpfenmwpgifvymvhrscgtscfelekl
crfimsvkknyrrvpyhnwkhavtvahcmyailqnnhtlftdlerkglliaclchdldhr
gfsnsytstmeqhhfsqtvsilqleghnifstlssseyeqvleiirkaiiatdlalyfgn
rkqleemyqtgslnlnnqshrdrviglmmtacdlcsvtklwpvtkltandiyaefwaegd
emkklgiqpipmmdrdkkdevpqgqlgfynavaipcyttltqilpptepllkacrdnlsq
wekvirge

Timeline for d3sn7b1:

• d3sn7b1 first appeared in SCOPe 2.03, called d3sn7b_
  
• d3sn7b1 appears in SCOPe 2.06
  
• d3sn7b1 appears in the current release, SCOPe 2.08