SCOPe 2.03: Domain d3sn7b_: 3sn7 B:

Lineage for d3sn7b_ (3sn7 B:)

1. Root: SCOPe 2.03

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
   multihelical; consists of two different alpha-helical bundles

4. Superfamily a.211.1: HD-domain/PDEase-like [109604] (6 families)

5. Family a.211.1.0: automated matches [191566] (1 protein)
   not a true family

6. Protein automated matches [190983] (4 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188676] (34 PDB entries)

8. Domain d3sn7b_: 3sn7 B: [233565]
   automated match to d3wi2a_
   complexed with 540, cl, mg, zn

Details for d3sn7b_

PDB Entry: 3sn7, 1.82 Å

PDB Description: highly potent, selective, and orally active phosphodiestarase 10a inhibitors

PDB Compounds: (B:) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

SCOPe Domain Sequences for d3sn7b_:

Sequence, based on SEQRES records:

>d3sn7b_ a.211.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
hmsictseewqglmqftlpvrlckeielfhfdigpfenmwpgifvymvhrscgtscfele
klcrfimsvkknyrrvpyhnwkhavtvahcmyailqnnhtlftdlerkglliaclchdld
hrgfsnsylqkfdhplaalyststmeqhhfsqtvsilqleghnifstlssseyeqvleii
rkaiiatdlalyfgnrkqleemyqtgslnlnnqshrdrviglmmtacdlcsvtklwpvtk
ltandiyaefwaegdemkklgiqpipmmdrdkkdevpqgqlgfynavaipcyttltqilp
ptepllkacrdnlsqwekvirge

Sequence, based on observed residues (ATOM records):

>d3sn7b_ a.211.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
hmsictseewqglmqftlpvrlckeielfhfdigpfenmwpgifvymvhrscgtscfele
klcrfimsvkknyrrvpyhnwkhavtvahcmyailqnnhtlftdlerkglliaclchdld
hrgfsnsytstmeqhhfsqtvsilqleghnifstlssseyeqvleiirkaiiatdlalyf
gnrkqleemyqtgslnlnnqshrdrviglmmtacdlcsvtklwpvtkltandiyaefwae
gdemkklgiqpipmmdrdkkdevpqgqlgfynavaipcyttltqilpptepllkacrdnl
sqwekvirge

Timeline for d3sn7b_:

• d3sn7b_ is new in SCOPe 2.03-stable
  
• d3sn7b_ appears in SCOPe 2.04
  
• d3sn7b_ appears in the current release, SCOPe 2.08, called d3sn7b1