Lineage for d3nfaa_ (3nfa A:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2122050Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
    3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest
  4. 2123751Superfamily c.55.3: Ribonuclease H-like [53098] (15 families) (S)
    consists of one domain of this fold
  5. 2124026Family c.55.3.2: Retroviral integrase, catalytic domain [53107] (2 protein domains)
  6. 2124148Protein automated matches [190209] (5 species)
    not a true protein
  7. 2124149Species Human immunodeficiency virus 1 [TaxId:11676] [186963] (62 PDB entries)
  8. 2124156Domain d3nfaa_: 3nfa A: [233021]
    automated match to d4ah9a_
    complexed with acy, cbj, so4

Details for d3nfaa_

PDB Entry: 3nfa (more details), 1.95 Å

PDB Description: Structural basis for a new mechanism of inhibition of HIV integrase identified by fragment screening and structure based design
PDB Compounds: (A:) integrase

SCOPe Domain Sequences for d3nfaa_:

Sequence, based on SEQRES records: (download)

>d3nfaa_ c.55.3.2 (A:) automated matches {Human immunodeficiency virus 1 [TaxId: 11676]}
spgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvhtd
ngsnftsttvkaacwwagikqedgipynpqsqgviesmnkelkkiigqvrdqaehlktav
qmavfihnhkrkggiggysagerivdiiatdiq

Sequence, based on observed residues (ATOM records): (download)

>d3nfaa_ c.55.3.2 (A:) automated matches {Human immunodeficiency virus 1 [TaxId: 11676]}
spgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvhtd
ngsnftsttvkaacwwagikqedgipynpqsqgviesmnkelkkiigqvrdqaehlktav
qmavfihnhkrkgysagerivdiiatdiq

SCOPe Domain Coordinates for d3nfaa_:

Click to download the PDB-style file with coordinates for d3nfaa_.
(The format of our PDB-style files is described here.)

Timeline for d3nfaa_: