SCOPe 2.08: Domain d3kafa2: 3kaf A:51-163

Lineage for d3kafa2 (3kaf A:51-163)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.26: FKBP-like [54533] (3 superfamilies)
   core: beta(2)-alpha-beta(2); antiparallel beta-sheet

4. Superfamily d.26.1: FKBP-like [54534] (4 families)

5. Family d.26.1.1: FKBP immunophilin/proline isomerase [54535] (17 proteins)

6. Protein Mitotic rotamase PIN1, domain 2 [54547] (2 species)
   Domain 1 is a WW-domain

7. Species Human (Homo sapiens) [TaxId:9606] [54548] (52 PDB entries)

8. Domain d3kafa2: 3kaf A:51-163 [232702]
   Other proteins in same PDB: d3kafa1
   automated match to d2xp6a2
   complexed with 4d9
   has additional insertions and/or extensions that are not grouped together

Details for d3kafa2

PDB Entry: 3kaf, 2.3 Å

PDB Description: structure-guided design of alpha-amino acid-derived pin1 inhibitors

PDB Compounds: (A:) Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1

SCOPe Domain Sequences for d3kafa2:

Sequence; same for both SEQRES and ATOM records:

>d3kafa2 d.26.1.1 (A:51-163) Mitotic rotamase PIN1, domain 2 {Human (Homo sapiens) [TaxId: 9606]}
eparvrcshllvkhsqsrrpsswrqekitrtkeealelingyiqkiksgeedfeslasqf
sdcssakargdlgafsrgqmakpfedasfalrtgemsgpvftdsgihiilrte

Timeline for d3kafa2:

• d3kafa2 first appeared in SCOPe 2.03
  
• d3kafa2 appears in SCOPe 2.07