Lineage for d3h8cb_ (3h8c B:)

  1. Root: SCOPe 2.04
  2. 1631855Class d: Alpha and beta proteins (a+b) [53931] (380 folds)
  3. 1634067Fold d.3: Cysteine proteinases [54000] (1 superfamily)
    consists of one alpha-helix and 4 strands of antiparallel beta-sheet and contains the catalytic triad Cys-His-Asn
  4. 1634068Superfamily d.3.1: Cysteine proteinases [54001] (23 families) (S)
    the constitute families differ by insertion into and circular permutation of the common catalytic core made of one alpha-helix and 3-strands of beta-sheet
  5. 1634821Family d.3.1.0: automated matches [191342] (1 protein)
    not a true family
  6. 1634822Protein automated matches [190230] (16 species)
    not a true protein
  7. 1634834Species Human (Homo sapiens) [TaxId:9606] [187072] (30 PDB entries)
  8. 1634870Domain d3h8cb_: 3h8c B: [232433]
    automated match to d2xu3a_
    complexed with nsz

Details for d3h8cb_

PDB Entry: 3h8c (more details), 2.5 Å

PDB Description: A combined crystallographic and molecular dynamics study of cathepsin-L retro-binding inhibitors (compound 14)
PDB Compounds: (B:) Cathepsin L1

SCOPe Domain Sequences for d3h8cb_:

Sequence, based on SEQRES records: (download)

>d3h8cb_ d.3.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
aprsvdwrekgyvtpvknqgqcgscwafsatgalegqmfrktgrlislseqnlvdcsgpq
gnegcngglmdyafqyvqdnggldseesypyeateesckynpkysvandtgfvdipkqek
almkavatvgpisvaidaghesflfykegiyfepdcssedmdhgvlvvgygfestesdnn
kywlvknswgeewgmggyvkmakdrrnhcgiasaasyptv

Sequence, based on observed residues (ATOM records): (download)

>d3h8cb_ d.3.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
aprsvdwrekgyvtpvknqgqcgscwafsatgalegqmfrktgrlislseqnlvdcsgpq
gnegcngglmdyafqyvqdnggldseesypyeateesckynpkysvandtgfvdipkqek
almkavatvgpisvaidaghesflfykegiyfepdcssedmdhgvlvvgygfesnkywlv
knswgeewgmggyvkmakdrrnhcgiasaasyptv

SCOPe Domain Coordinates for d3h8cb_:

Click to download the PDB-style file with coordinates for d3h8cb_.
(The format of our PDB-style files is described here.)

Timeline for d3h8cb_:

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d3h8ca_