SCOPe 2.08: Domain d3h1da1: 3h1d A:3993-4366

Lineage for d3h1da1 (3h1d A:3993-4366)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.148: Hect, E3 ligase catalytic domain [56203] (1 superfamily)
   consists of two alpha+beta domains; the N-terminal domain is array of helices and beta-hairpins; the C-terminal domain is an a/b sandwich with one left-handed beta-alpha(n)-beta unit; conformational flexibility of domain orientation

4. Superfamily d.148.1: Hect, E3 ligase catalytic domain [56204] (2 families)
   automatically mapped to Pfam PF00632

5. Family d.148.1.0: automated matches [227207] (1 protein)
   not a true family

6. Protein automated matches [226939] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [225255] (18 PDB entries)

8. Domain d3h1da1: 3h1d A:3993-4366 [232357]
   Other proteins in same PDB: d3h1da2
   automated match to d2onia_
   complexed with so4

Details for d3h1da1

PDB Entry: 3h1d, 1.89 Å

PDB Description: structure of the huwe1 hect domain

PDB Compounds: (A:) E3 ubiquitin-protein ligase HUWE1

SCOPe Domain Sequences for d3h1da1:

Sequence, based on SEQRES records:

>d3h1da1 d.148.1.0 (A:3993-4366) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dfdvkrkyfrqelerldeglrkedmavhvrrdhvfedsyrelhrkspeemknrlyivfeg
eegqdaggllrewymiisremfnpmyalfrtspgdrvtytinpsshanpnhlsyfkfvgr
ivakavydnrllecyftrsfykhilgksvrytdmesedyhfyqglvyllendvstlgydl
tfstevqefgvaevrdlkpnganilvteenkkeyvhlvcqmrmtgairkqlaaflegfye
iipkrlisifteqelellisglptididdlksnteyhkyqsnsiqiqwfwralrsfdqad
rakflqfvtgtskvplqgfaalegmngiqkfqihrddrstdrlpsahtcfnqldlpayes
feklrhmlllaiqe

Sequence, based on observed residues (ATOM records):

>d3h1da1 d.148.1.0 (A:3993-4366) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dfdvkrkyfrqelerldeglrkedmavhvrrdhvfedsyrelhrkspeemknrlyivfeg
eegqdaggllrewymiisremfnpmyalfrtspgdrvtytinpsnhlsyfkfvgrivaka
vydnrllecyftrsfykhilgksvrytdmesedyhfyqglvyllendvstlgydltfste
vqefgvaevrdlkpnganilvteenkkeyvhlvcqmrmtgairkqlaaflegfyeiipkr
lisifteqelellisglptididdlksnteyhkyqsnsiqiqwfwralrsfdqadrakfl
qfvtgtskvplqgfaalegmngiqkfqihrddrstdrlpsahtcfnqldlpayesfeklr
hmlllaiqe

Timeline for d3h1da1:

• d3h1da1 first appeared in SCOPe 2.03, called d3h1da_
  
• d3h1da1 appears in SCOPe 2.07