SCOPe 2.08: Domain d3d7ta_: 3d7t A:

Lineage for d3d7ta_ (3d7t A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Carboxyl-terminal src kinase (csk) [56164] (1 species)
   PTK group; CSK subfamily; non-membrane spanning protein tyrosine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [56165] (4 PDB entries)

8. Domain d3d7ta_: 3d7t A: [231928]
   Other proteins in same PDB: d3d7tb_
   automated match to d3js2a_
   complexed with stu

Details for d3d7ta_

PDB Entry: 3d7t, 2.9 Å

PDB Description: structural basis for the recognition of c-src by its inactivator csk

PDB Compounds: (A:) Tyrosine-protein kinase CSK

SCOPe Domain Sequences for d3d7ta_:

Sequence, based on SEQRES records:

>d3d7ta_ d.144.1.7 (A:) Carboxyl-terminal src kinase (csk) {Human (Homo sapiens) [TaxId: 9606]}
walnmkelkllqtigkgefgdvmlgdyrgnkvavkcikndataqaflaeasvmtqlrhsn
lvqllgviveekgglyivteymakgslvdylrsrgrsvlggdcllkfsldvceameyleg
nnfvhrdlaarnvlvsednvakvsdfgltkeasstqdtgklpvkwtapealreaafstks
dvwsfgillweiysfgrvpypriplkdvvprvekgykmdapdgcppavyevmkncwhlda
amrpsflqlreqlehikthelhl

Sequence, based on observed residues (ATOM records):

>d3d7ta_ d.144.1.7 (A:) Carboxyl-terminal src kinase (csk) {Human (Homo sapiens) [TaxId: 9606]}
walnmkelkllqtigkgefgdvmlgdyrgnkvavkcikndataqaflaeasvmtqlrhsn
lvqllgviveekgglyivteymakgslvdylrsrgrsvlggdcllkfsldvceameyleg
nnfvhrdlaarnvlvsednvakvsdfgpvkwtapealreaafstksdvwsfgillweiys
fgrvpypriplkdvvprvekgykmdapdgcppavyevmkncwhldaamrpsflqlreqle
hikthelhl

Timeline for d3d7ta_:

• d3d7ta_ first appeared in SCOPe 2.03
  
• d3d7ta_ appears in SCOPe 2.07