SCOP 1.61: Domain d1he8a2: 1he8 A:353-524

Lineage for d1he8a2 (1he8 A:353-524)

1. Root: SCOP 1.61

2. Class b: All beta proteins [48724] (111 folds)

3. Fold b.7: C2 domain-like [49561] (4 superfamilies)

4. Superfamily b.7.1: C2 domain (Calcium/lipid-binding domain, CaLB) [49562] (2 families)

5. Family b.7.1.1: PLC-like (P variant) [49563] (6 proteins)

6. Protein Phoshoinositide 3-kinase (PI3K) [49570] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [49572] (3 PDB entries)

8. Domain d1he8a2: 1he8 A:353-524 [23189]
   Other proteins in same PDB: d1he8a1, d1he8a3, d1he8a4, d1he8b_

Details for d1he8a2

PDB Entry: 1he8, 3 Å

PDB Description: ras g12v - pi 3-kinase gamma complex

SCOP Domain Sequences for d1he8a2:

Sequence, based on SEQRES records:

>d1he8a2 b.7.1.1 (A:353-524) Phoshoinositide 3-kinase (PI3K) {Human (Homo sapiens)}
slwdcdrkfrvkirgidipvlprntdltvfveaniqhgqqvlcqrrtspkpfteevlwnv
wlefsikikdlpkgallnlqiycgkapalsskasaespsseskgkvrllyyvnlllidhr
fllrrgeyvlhmwqisgkgedqgsfnadkltsatnpdkensmsisilldnyc

Sequence, based on observed residues (ATOM records):

>d1he8a2 b.7.1.1 (A:353-524) Phoshoinositide 3-kinase (PI3K) {Human (Homo sapiens)}
slwdcdrkfrvkirgidipvlpltvfveaniqhgqqvlcqrrtspkpfteevlwnvwlef
sikikdlpkgallnlqiyckvrllyyvnlllidhrfllrrgeyvlhmwqisnadkltsat
npdkensmsisilldnyc

Timeline for d1he8a2:

• d1he8a2 first appeared (with stable ids) in SCOP 1.55
  
• d1he8a2 appears in SCOP 1.59
  
• d1he8a2 appears in SCOP 1.63
  
• d1he8a2 appears in the current release, SCOPe 2.08