Lineage for d1e8ya2 (1e8y A:357-522)

  1. Root: SCOP 1.61
  2. 157351Class b: All beta proteins [48724] (111 folds)
  3. 163036Fold b.7: C2 domain-like [49561] (4 superfamilies)
  4. 163037Superfamily b.7.1: C2 domain (Calcium/lipid-binding domain, CaLB) [49562] (2 families) (S)
  5. 163038Family b.7.1.1: PLC-like (P variant) [49563] (6 proteins)
  6. 163052Protein Phoshoinositide 3-kinase (PI3K) [49570] (2 species)
  7. 163053Species Human (Homo sapiens) [TaxId:9606] [49572] (3 PDB entries)
  8. 163054Domain d1e8ya2: 1e8y A:357-522 [23187]
    Other proteins in same PDB: d1e8ya1, d1e8ya3, d1e8ya4

Details for d1e8ya2

PDB Entry: 1e8y (more details), 2 Å

PDB Description: structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, ly294002, quercetin, myricetin and staurosporine

SCOP Domain Sequences for d1e8ya2:

Sequence, based on SEQRES records: (download)

>d1e8ya2 b.7.1.1 (A:357-522) Phoshoinositide 3-kinase (PI3K) {Human (Homo sapiens)}
cdrkfrvkirgidipvlprntdltvfveaniqhgqqvlcqrrtspkpfteevlwnvwlef
sikikdlpkgallnlqiycgkapalsskasaespsseskgkvrllyyvnlllidhrfllr
rgeyvlhmwqisgkgedqgsfnadkltsatnpdkensmsisilldn

Sequence, based on observed residues (ATOM records): (download)

>d1e8ya2 b.7.1.1 (A:357-522) Phoshoinositide 3-kinase (PI3K) {Human (Homo sapiens)}
cdrkfrvkirgidipvlprntdltvfveaniqhgqqvlcqrrtspkpfteevlwnvwlef
sikikdlpkgallnlqiycllyyvnlllidhrfllrrgeyvlhmwqisgfnadkltsatn
pdkensmsisilldn

SCOP Domain Coordinates for d1e8ya2:

Click to download the PDB-style file with coordinates for d1e8ya2.
(The format of our PDB-style files is described here.)

Timeline for d1e8ya2: