SCOP 1.59: Domain d1e90a2: 1e90 A:357-521

Lineage for d1e90a2 (1e90 A:357-521)

1. Root: SCOP 1.59

2. Class b: All beta proteins [48724] (110 folds)

3. Fold b.7: C2 domain-like [49561] (4 superfamilies)

4. Superfamily b.7.1: C2 domain (Calcium/lipid-binding domain, CaLB) [49562] (2 families)

5. Family b.7.1.1: PLC-like (P variant) [49563] (6 proteins)

6. Protein Phoshoinositide 3-kinase (PI3K) [49570] (2 species)

7. Species Pig (Sus scrofa) [TaxId:9823] [49571] (5 PDB entries)

8. Domain d1e90a2: 1e90 A:357-521 [23185]
   Other proteins in same PDB: d1e90a1, d1e90a3, d1e90a4

Details for d1e90a2

PDB Entry: 1e90, 2.7 Å

PDB Description: structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, ly294002, quercetin, myricetin and staurosporine

SCOP Domain Sequences for d1e90a2:

Sequence, based on SEQRES records:

>d1e90a2 b.7.1.1 (A:357-521) Phoshoinositide 3-kinase (PI3K) {Pig (Sus scrofa)}
cdrkfrvkirgidipvlprtadltvfveaniqygqqvlcqrrtspkpfteevlwnvwlef
sikikdlpkgallnlqiycgkapalsgktsaempspeskgkaqllyyvnlllidhrfllr
hgeyvlhmwqlsgkgedqgsfnadkltsatnpdkensmsisilld

Sequence, based on observed residues (ATOM records):

>d1e90a2 b.7.1.1 (A:357-521) Phoshoinositide 3-kinase (PI3K) {Pig (Sus scrofa)}
cdrkfrvkirgidipvlprtadltvfveaniqygqqvlcqrrtspkpfteevlwnvwlef
sikikdlpkgallnlqiycqllyyvnlllidhrfllrhgeyvlhmwqlsfnadkltsatn
pdkensmsisilld

Timeline for d1e90a2:

• d1e90a2 first appeared (with stable ids) in SCOP 1.55
  
• d1e90a2 appears in SCOP 1.57
  
• d1e90a2 appears in SCOP 1.61
  
• d1e90a2 appears in the current release, SCOPe 2.08