SCOP 1.59: Domain d1e7va2: 1e7v A:354-524

Lineage for d1e7va2 (1e7v A:354-524)

1. Root: SCOP 1.59

2. Class b: All beta proteins [48724] (110 folds)

3. Fold b.7: C2 domain-like [49561] (4 superfamilies)

4. Superfamily b.7.1: C2 domain (Calcium/lipid-binding domain, CaLB) [49562] (2 families)

5. Family b.7.1.1: PLC-like (P variant) [49563] (6 proteins)

6. Protein Phoshoinositide 3-kinase (PI3K) [49570] (2 species)

7. Species Pig (Sus scrofa) [TaxId:9823] [49571] (5 PDB entries)

8. Domain d1e7va2: 1e7v A:354-524 [23184]
   Other proteins in same PDB: d1e7va1, d1e7va3, d1e7va4

Details for d1e7va2

PDB Entry: 1e7v, 2.4 Å

PDB Description: structure determinants of phosphoinositide 3-kinase inhibition by wortmannin, ly294002, quercetin, myricetin and staurosporine

SCOP Domain Sequences for d1e7va2:

Sequence, based on SEQRES records:

>d1e7va2 b.7.1.1 (A:354-524) Phoshoinositide 3-kinase (PI3K) {Pig (Sus scrofa)}
lwdcdrkfrvkirgidipvlprtadltvfveaniqygqqvlcqrrtspkpfteevlwnvw
lefsikikdlpkgallnlqiycgkapalsgktsaempspeskgkaqllyyvnlllidhrf
llrhgeyvlhmwqlsgkgedqgsfnadkltsatnpdkensmsisilldnyc

Sequence, based on observed residues (ATOM records):

>d1e7va2 b.7.1.1 (A:354-524) Phoshoinositide 3-kinase (PI3K) {Pig (Sus scrofa)}
lwdcdrkfrvkirgidipvlprtadltvfveaniqygqqvlcqrrtspkpfteevlwnvw
lefsikikdlpkgallnlqiycqllyyvnlllidhrfllrhgeyvlhmwqlsfnadklts
atnpdkensmsisilldnyc

Timeline for d1e7va2:

• d1e7va2 first appeared (with stable ids) in SCOP 1.55
  
• d1e7va2 appears in SCOP 1.57
  
• d1e7va2 appears in SCOP 1.61
  
• d1e7va2 appears in the current release, SCOPe 2.08