SCOP 1.59: Domain d1e8xa2: 1e8x A:357-522

Lineage for d1e8xa2 (1e8x A:357-522)

1. Root: SCOP 1.59

2. Class b: All beta proteins [48724] (110 folds)

3. Fold b.7: C2 domain-like [49561] (4 superfamilies)

4. Superfamily b.7.1: C2 domain (Calcium/lipid-binding domain, CaLB) [49562] (2 families)

5. Family b.7.1.1: PLC-like (P variant) [49563] (6 proteins)

6. Protein Phoshoinositide 3-kinase (PI3K) [49570] (2 species)

7. Species Pig (Sus scrofa) [TaxId:9823] [49571] (5 PDB entries)

8. Domain d1e8xa2: 1e8x A:357-522 [23183]
   Other proteins in same PDB: d1e8xa1, d1e8xa3, d1e8xa4

Details for d1e8xa2

PDB Entry: 1e8x, 2.2 Å

PDB Description: structural insights into phoshoinositide 3-kinase enzymatic mechanism and signalling

SCOP Domain Sequences for d1e8xa2:

Sequence, based on SEQRES records:

>d1e8xa2 b.7.1.1 (A:357-522) Phoshoinositide 3-kinase (PI3K) {Pig (Sus scrofa)}
cdrkfrvkirgidipvlprtadltvfveaniqygqqvlcqrrtspkpfteevlwnvwlef
sikikdlpkgallnlqiycgkapalsgktsaempspeskgkaqllyyvnlllidhrfllr
hgeyvlhmwqlsgkgedqgsfnadkltsatnpdkensmsisilldn

Sequence, based on observed residues (ATOM records):

>d1e8xa2 b.7.1.1 (A:357-522) Phoshoinositide 3-kinase (PI3K) {Pig (Sus scrofa)}
cdrkfrvkirgidipvlprtadltvfveaniqygqqvlcqrrtspkpfteevlwnvwlef
sikikdlpkgallnlqiycqllyyvnlllidhrfllrhgeyvlhmwqlsgfnadkltsat
npdkensmsisilldn

Timeline for d1e8xa2:

• d1e8xa2 first appeared (with stable ids) in SCOP 1.55
  
• d1e8xa2 appears in SCOP 1.57
  
• d1e8xa2 appears in SCOP 1.61
  
• d1e8xa2 appears in the current release, SCOPe 2.08