SCOPe 2.06: Domain d1d5ra1: 1d5r A:188-351

Lineage for d1d5ra1 (1d5r A:188-351)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.7: C2 domain-like [49561] (5 superfamilies)
   sandwich; 8 strands in 2 sheets; greek-key

4. Superfamily b.7.1: C2 domain (Calcium/lipid-binding domain, CaLB) [49562] (3 families)
   two constituent families are related by circular permutation

5. Family b.7.1.1: PLC-like (P variant) [49563] (12 proteins)

6. Protein Pten tumor suppressor (Phoshphoinositide phosphatase), C-terminal domain [49568] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [49569] (1 PDB entry)

8. Domain d1d5ra1: 1d5r A:188-351 [23181]
   Other proteins in same PDB: d1d5ra2
   complexed with tla

Details for d1d5ra1

PDB Entry: 1d5r, 2.1 Å

PDB Description: crystal structure of the pten tumor suppressor

PDB Compounds: (A:) phosphoinositide phosphotase pten

SCOPe Domain Sequences for d1d5ra1:

Sequence, based on SEQRES records:

>d1d5ra1 b.7.1.1 (A:188-351) Pten tumor suppressor (Phoshphoinositide phosphatase), C-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
yrpvallfhkmmfetipmfsggtcnpqfvvcqlkvkiyssnsgptrredkfmyfefpqpl
pvcgdikveffhkqnkmlkkdkmfhfwvntffipgpeevdndkeylvltltkndldkank
dkanryfspnfkvklyftktv

Sequence, based on observed residues (ATOM records):

>d1d5ra1 b.7.1.1 (A:188-351) Pten tumor suppressor (Phoshphoinositide phosphatase), C-terminal domain {Human (Homo sapiens) [TaxId: 9606]}
yrpvallfhkmmfetipmfsggtcnpqfvvcqlkvkiyssnsgptrredkfmyfefpqpl
pvcgdikveffhkqnkmlkkdkmfhfwvntffipkeylvltltkndldkankdkanryfs
pnfkvklyftktv

Timeline for d1d5ra1:

• d1d5ra1 first appeared (with stable ids) in SCOP 1.55
  
• d1d5ra1 appears in SCOPe 2.05
  
• d1d5ra1 appears in SCOPe 2.07
  
• d1d5ra1 appears in the current release, SCOPe 2.08