SCOPe 2.08: Domain d2w8ra_: 2w8r A:

Lineage for d2w8ra_ (2w8r A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.82: ALDH-like [53719] (1 superfamily)
   consists of two similar domains with 3 layers (a/b/a) each; duplication
   core: parallel beta-sheet of 5 strands, order 32145

4. Superfamily c.82.1: ALDH-like [53720] (3 families)
   binds NAD differently from other NAD(P)-dependent oxidoreductases

5. Family c.82.1.0: automated matches [191448] (1 protein)
   not a true family

6. Protein automated matches [190683] (61 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [225691] (37 PDB entries)

8. Domain d2w8ra_: 2w8r A: [231375]
   automated match to d2w8na_
   complexed with adp, gol, so4

Details for d2w8ra_

PDB Entry: 2w8r, 2.4 Å

PDB Description: The crystal structure of human SSADH in complex with NAD+

PDB Compounds: (A:) succinate-semialdehyde dehydrogenase, mitochondrial

SCOPe Domain Sequences for d2w8ra_:

Sequence; same for both SEQRES and ATOM records:

>d2w8ra_ c.82.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
laglsaallrtdsfvggrwlpaaatfpvqdpasgaalgmvadcgvrearaavraayeafc
rwrevsakerssllrkwynlmiqnkddlariitaesgkplkeahgeilysafflewfsee
arrvygdiihtpakdrralvlkqpigvaavitpwnfpsamitrkvgaalaagctvvvkpa
edtpfsalalaelasqagipsgvynvipcsrknakevgeaictdplvskisftgstttgk
illhhaansvkrvsmelgglapfivfdsanvdqavagamaskfrntgqtavcsnqflvqr
gihdafvkafaeamkknlrvgngfeegttqgplinekavekvekqvndavskgatvvtgg
krhqlgknffeptllcnvtqdmlctheetfgplapvikfdteeeaiaianaadvglagyf
ysqdpaqiwrvaeqlevgmvgvneglissvecpfggvkqsglgregskygideylelkyv
cyggl

Timeline for d2w8ra_:

• d2w8ra_ first appeared in SCOPe 2.03
  
• d2w8ra_ appears in SCOPe 2.07