SCOPe 2.06: Domain d2w1ia_: 2w1i A:

Lineage for d2w1ia_ (2w1i A:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (25 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (882 PDB entries)

8. Domain d2w1ia_: 2w1i A: [231371]
   automated match to d4gmya_
   complexed with l0i

Details for d2w1ia_

PDB Entry: 2w1i, 2.6 Å

PDB Description: structure determination of aurora kinase in complex with inhibitor

PDB Compounds: (A:) jak2

SCOPe Domain Sequences for d2w1ia_:

Sequence, based on SEQRES records:

>d2w1ia_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qfeerhlkflqqlgkgnfgsvemcrydplqdntgevvavkklqhsteehlrdfereieil
kslqhdnivkykgvcysagrrnlklimeylpygslrdylqkhkeridhikllqytsqick
gmeylgtkryihrdlatrnilvenenrvkigdfgltkvlpqdkeyykvkepgespifwya
peslteskfsvasdvwsfgvvlyelftyieksksppaefmrmigndkqgqmivfhliell
knngrlprpdgcpdeiymimtecwnnnvnqrpsfrdlalrvdqirdqmag

Sequence, based on observed residues (ATOM records):

>d2w1ia_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qfeerhlkflqqlgkgnfgsvemcrydplqdntgevvavkklqhsteehlrdfereieil
kslqhdnivkykgvcysnlklimeylpygslrdylqkhkeridhikllqytsqickgmey
lgtkryihrdlatrnilvenenrvkigdfgltkvlpqdkeyykvkepgespifwyapesl
teskfsvasdvwsfgvvlyelftyieksksppaefmrmigndkqgqmivfhliellknng
rlprpdgcpdeiymimtecwnnnvnqrpsfrdlalrvdqirdqmag

Timeline for d2w1ia_:

• d2w1ia_ first appeared in SCOPe 2.03
  
• d2w1ia_ appears in SCOPe 2.05
  
• d2w1ia_ appears in SCOPe 2.07
  
• d2w1ia_ appears in the current release, SCOPe 2.08