Lineage for d2v7aa_ (2v7a A:)

  1. Root: SCOPe 2.06
  2. 2170735Class d: Alpha and beta proteins (a+b) [53931] (385 folds)
  3. 2218047Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 2218048Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 2218179Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 2220941Protein automated matches [190091] (17 species)
    not a true protein
  7. 2221040Species Human (Homo sapiens) [TaxId:9606] [188447] (653 PDB entries)
  8. 2221826Domain d2v7aa_: 2v7a A: [231313]
    automated match to d2v7ab_
    complexed with 627, mg; mutant

Details for d2v7aa_

PDB Entry: 2v7a (more details), 2.5 Å

PDB Description: crystal structure of the t315i abl mutant in complex with the inhibitor pha-739358
PDB Compounds: (A:) Proto-oncogene tyrosine-protein kinase ABL1

SCOPe Domain Sequences for d2v7aa_:

Sequence; same for both SEQRES and ATOM records: (download)

>d2v7aa_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dkwemertditmkhklgggqygevyegvwkkysltvavktlkedtmeveeflkeaavmke
ikhpnlvqllgvctreppfyiiiefmtygnlldylrecnrqevnavvllymatqissame
ylekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfpikwtapesla
ynkfsiksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpegcpekvyelm
racwqwnpsdrpsfaeihqafetmfqessis

SCOPe Domain Coordinates for d2v7aa_:

Click to download the PDB-style file with coordinates for d2v7aa_.
(The format of our PDB-style files is described here.)

Timeline for d2v7aa_:

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d2v7ab_