SCOPe 2.03: Domain d2v7aa_: 2v7a A:

Lineage for d2v7aa_ (2v7a A:)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (11 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (418 PDB entries)

8. Domain d2v7aa_: 2v7a A: [231313]
   automated match to d2v7ab_

Details for d2v7aa_

PDB Entry: 2v7a, 2.5 Å

PDB Description: crystal structure of the t315i abl mutant in complex with the inhibitor pha-739358

PDB Compounds: (A:) Proto-oncogene tyrosine-protein kinase ABL1

SCOPe Domain Sequences for d2v7aa_:

Sequence; same for both SEQRES and ATOM records:

>d2v7aa_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dkwemertditmkhklgggqygevyegvwkkysltvavktlkedtmeveeflkeaavmke
ikhpnlvqllgvctreppfyiiiefmtygnlldylrecnrqevnavvllymatqissame
ylekknfihrdlaarnclvgenhlvkvadfglsrlmtgdtytahagakfpikwtapesla
ynkfsiksdvwafgvllweiatygmspypgidlsqvyellekdyrmerpegcpekvyelm
racwqwnpsdrpsfaeihqafetmfqessis

Timeline for d2v7aa_:

• d2v7aa_ is new in SCOPe 2.03-stable
  
• d2v7aa_ appears in SCOPe 2.04
  
• d2v7aa_ appears in the current release, SCOPe 2.08