SCOPe 2.03: Domain d2qcta_: 2qct A:

Lineage for d2qcta_ (2qct A:)

1. Root: SCOPe 2.03

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.45: (Phosphotyrosine protein) phosphatases II [52798] (1 superfamily)
   core: 3 layers, a/b/a; parallel beta-sheet of 4 strands, order 1423

4. Superfamily c.45.1: (Phosphotyrosine protein) phosphatases II [52799] (6 families)
   share with the family I the common active site structure with a circularly permuted topology

5. Family c.45.1.0: automated matches [191381] (1 protein)
   not a true family

6. Protein automated matches [190475] (5 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187400] (65 PDB entries)

8. Domain d2qcta_: 2qct A: [231198]
   automated match to d3h2xa_
   complexed with 561, edo

Details for d2qcta_

PDB Entry: 2qct, 2.8 Å

PDB Description: Structure of Lyp with inhibitor I-C11

PDB Compounds: (A:) Tyrosine-protein phosphatase non-receptor type 22

SCOPe Domain Sequences for d2qcta_:

Sequence, based on SEQRES records:

>d2qcta_ c.45.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qreilqkfldeaqskkitkeefaneflklkrqstkykadktypttvaekpknikknrykd
ilpydysrvelslitsdedssyinanfikgvygpkayiatqgplsttlldfwrmiweysv
liivmacmeyemgkkkcerywaepgemqlefgpfsvsceaekrksdyiirtlkvkfnset
rtiyqfhyknwpdhdvpssidpileliwdvrcyqeddsvpicihcsagcgrtgvicaidy
twmllkdgiipenfsvfsliremrtqrpslvqtqeqyelvynavlelfkrqm

Sequence, based on observed residues (ATOM records):

>d2qcta_ c.45.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
qreilqkfldefaneflklkrqstkykadktypttvaekpknikknrykdilpydysrve
lslitsdedssyinanfikgvygpkayiatqgplsttlldfwrmiweysvliivmacmey
emgkkkcerywaepgemqlefgpfsvsceaekrksdyiirtlkvkfnsetrtiyqfhykn
wpdhdvpssidpileliwdvrcyqeddsvpicihcsagcgrtgvicaidytwmllkdgii
penfsvfsliremrtqrpslvqtqeqyelvynavlelfkrqm

Timeline for d2qcta_:

• d2qcta_ is new in SCOPe 2.03-stable
  
• d2qcta_ appears in SCOPe 2.04
  
• d2qcta_ appears in the current release, SCOPe 2.08