SCOPe 2.07: Domain d2ourb1: 2our B:449-776

Lineage for d2ourb1 (2our B:449-776)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
   multihelical; consists of two different alpha-helical bundles

4. Superfamily a.211.1: HD-domain/PDEase-like [109604] (6 families)

5. Family a.211.1.0: automated matches [191566] (1 protein)
   not a true family

6. Protein automated matches [190983] (10 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188676] (136 PDB entries)

8. Domain d2ourb1: 2our B:449-776 [231108]
   Other proteins in same PDB: d2oura2, d2ourb2
   automated match to d3wi2a_
   complexed with cmp, mg; mutant

Details for d2ourb1

PDB Entry: 2our, 1.45 Å

PDB Description: crystal structure of pde10a2 mutant d674a in complex with camp

PDB Compounds: (B:) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

SCOPe Domain Sequences for d2ourb1:

Sequence, based on SEQRES records:

>d2ourb1 a.211.1.0 (B:449-776) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sictseewqglmqftlpvrlckeielfhfdigpfenmwpgifvymvhrscgtscfelekl
crfimsvkknyrrvpyhnwkhavtvahcmyailqnnhtlftdlerkglliaclchdldhr
gfsnsylqkfdhplaalyststmeqhhfsqtvsilqleghnifstlssseyeqvleiirk
aiiatdlalyfgnrkqleemyqtgslnlnnqshrdrviglmmtacalcsvtklwpvtklt
andiyaefwaegdemkklgiqpipmmdrdkkdevpqgqlgfynavaipcyttltqilppt
epllkacrdnlsqwekvirgeetatwis

Sequence, based on observed residues (ATOM records):

>d2ourb1 a.211.1.0 (B:449-776) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sictseewqglmqftlpvrlckeielfhfdigpfenmwpgifvymvhrscgtscfelekl
crfimsvkknyrrvpyhnwkhavtvahcmyailqnnhtlftdlerkglliaclchdldhr
gfststmeqhhfsqtvsilqleghnifstlssseyeqvleiirkaiiatdlalyfgnrkq
leemyqtgslnlnnqshrdrviglmmtacalcsvtklwpvtkltandiyaefwaegdemk
klgiqpipmmdrdkkdevpqgqlgfynavaipcyttltqilpptepllkacrdnlsqwek
virgeetatwis

Timeline for d2ourb1:

• d2ourb1 first appeared in SCOPe 2.03, called d2ourb_
  
• d2ourb1 appears in SCOPe 2.06
  
• d2ourb1 appears in the current release, SCOPe 2.08