Lineage for d2ourb1 (2our B:449-776)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 2014835Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
    multihelical; consists of two different alpha-helical bundles
  4. 2014836Superfamily a.211.1: HD-domain/PDEase-like [109604] (6 families) (S)
  5. 2015250Family a.211.1.0: automated matches [191566] (1 protein)
    not a true family
  6. 2015251Protein automated matches [190983] (9 species)
    not a true protein
  7. 2015252Species Human (Homo sapiens) [TaxId:9606] [188676] (111 PDB entries)
  8. 2015256Domain d2ourb1: 2our B:449-776 [231108]
    Other proteins in same PDB: d2oura2, d2ourb2
    automated match to d3wi2a_
    complexed with cmp, mg; mutant

Details for d2ourb1

PDB Entry: 2our (more details), 1.45 Å

PDB Description: crystal structure of PDE10A2 mutant D674A in complex with cAMP
PDB Compounds: (B:) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

SCOPe Domain Sequences for d2ourb1:

Sequence, based on SEQRES records: (download)

>d2ourb1 a.211.1.0 (B:449-776) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sictseewqglmqftlpvrlckeielfhfdigpfenmwpgifvymvhrscgtscfelekl
crfimsvkknyrrvpyhnwkhavtvahcmyailqnnhtlftdlerkglliaclchdldhr
gfsnsylqkfdhplaalyststmeqhhfsqtvsilqleghnifstlssseyeqvleiirk
aiiatdlalyfgnrkqleemyqtgslnlnnqshrdrviglmmtacalcsvtklwpvtklt
andiyaefwaegdemkklgiqpipmmdrdkkdevpqgqlgfynavaipcyttltqilppt
epllkacrdnlsqwekvirgeetatwis

Sequence, based on observed residues (ATOM records): (download)

>d2ourb1 a.211.1.0 (B:449-776) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sictseewqglmqftlpvrlckeielfhfdigpfenmwpgifvymvhrscgtscfelekl
crfimsvkknyrrvpyhnwkhavtvahcmyailqnnhtlftdlerkglliaclchdldhr
gfststmeqhhfsqtvsilqleghnifstlssseyeqvleiirkaiiatdlalyfgnrkq
leemyqtgslnlnnqshrdrviglmmtacalcsvtklwpvtkltandiyaefwaegdemk
klgiqpipmmdrdkkdevpqgqlgfynavaipcyttltqilpptepllkacrdnlsqwek
virgeetatwis

SCOPe Domain Coordinates for d2ourb1:

Click to download the PDB-style file with coordinates for d2ourb1.
(The format of our PDB-style files is described here.)

Timeline for d2ourb1:

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Domains from same chain:
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d2ourb2