SCOPe 2.03: Domain d2iwib_: 2iwi B:

Lineage for d2iwib_ (2iwi B:)

1. Root: SCOPe 2.03

2. Class d: Alpha and beta proteins (a+b) [53931] (376 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (18 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (314 PDB entries)

8. Domain d2iwib_: 2iwi B: [230868]
   automated match to d1zyda_
   complexed with hb1

Details for d2iwib_

PDB Entry: 2iwi, 2.8 Å

PDB Description: crystal structure of the human pim2 in complex with a ruthenium organometallic ligand ru1

PDB Compounds: (B:) serine/threonine-protein kinase pim-2

SCOPe Domain Sequences for d2iwib_:

Sequence, based on SEQRES records:

>d2iwib_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gkdreafeaeyrlgpllgkggfgtvfaghrltdrlqvaikviprnrvlgwsplsdsvtcp
levallwkvgaggghpgvirlldwfetqegfmlvlerplpaqdlfdyitekgplgegpsr
cffgqvvaaiqhchsrgvvhrdikdenilidlrrgcaklidfgsgallhdepytdfdgtr
vysppewisrhqyhalpatvwslgillydmvcgdipferdqeileaelhfpahvspdcca
lirrclapkpssrpsleeilldpwmq

Sequence, based on observed residues (ATOM records):

>d2iwib_ d.144.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gkdreafeaeyrlgpllgkggfgtvfaghrltdrlqvaikviprtcplevallwkvgagg
ghpgvirlldwfefmlvlerplpaqdlfdyitekgplgegpsrcffgqvvaaiqhchsrg
vvhrdikdenilidlrrgcaklidfgsgallhdepytdfdgtrvysppewisrhqyhalp
atvwslgillydmvcgdipferdqeileaelhfpahvspdccalirrclapkpssrpsle
eilldpwmq

Timeline for d2iwib_:

• d2iwib_ is new in SCOPe 2.03-stable
  
• d2iwib_ appears in SCOPe 2.04
  
• d2iwib_ appears in the current release, SCOPe 2.08