Lineage for d4ncsa_ (4ncs A:)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2064980Fold b.68: 6-bladed beta-propeller [50938] (11 superfamilies)
    consists of six 4-stranded beta-sheet motifs; meander
  4. 2064981Superfamily b.68.1: Sialidases [50939] (3 families) (S)
  5. 2064982Family b.68.1.1: Sialidases (neuraminidases) [50940] (10 protein domains)
  6. 2065266Protein automated matches [193245] (14 species)
    not a true protein
  7. 2065267Species Human (Homo sapiens) [TaxId:9606] [228885] (2 PDB entries)
  8. 2065268Domain d4ncsa_: 4ncs A: [230156]
    automated match to d4nc5a_
    complexed with fsr, po4

Details for d4ncsa_

PDB Entry: 4ncs (more details), 2.2 Å

PDB Description: human sialidase 2 in complex with 2,3-difluorosialic acid (covalent intermediate)
PDB Compounds: (A:) Sialidase-2

SCOPe Domain Sequences for d4ncsa_:

Sequence, based on SEQRES records: (download)

>d4ncsa_ b.68.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
aslpvlqkesvfqsgahayripallylpgqqsllafaeqraskkaehaelivlrrgdyda
pthqvqwqaqevvaqarldghrsmnpcplydaqtgtlflffiaipgqvteqqqlqtranv
trlcqvtstdhgrtwssprdltdaaigpayrewstfavgpghclqlndrarslvvpayay
rklhpiqrpipsafcflshdhgrtwarghfvaqdtlecqvaevetgeqrvvtlnarshlr
arvqaqstndgldfqesqlvkklvepppqgcqgsvisfpsprsgpgspaqwllythpths
wqradlgaylnprppapeawsepvllakgscaysdlqsmgtgpdgsplfgclyeandyee
ivflmftlkqafpaey

Sequence, based on observed residues (ATOM records): (download)

>d4ncsa_ b.68.1.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
aslpvlqkesvfqsgahayripallylpgqqsllafaeqraaelivlrrgdydapthqvq
wqaqevvaqarldghrsmnpcplydaqtgtlflffiaipganvtrlcqvtstdhgrtwss
prdltdaaigpayrewstfavgpghclqlndrarslvvpayayrklhpiqrpipsafcfl
shdhgrtwarghfvaqdtlecqvaeveqrvvtlnarshlrarvqaqstndgldfqesqlv
kklvepppqgcqgsvisfpspraqwllythpthswqradlgaylnprppapeawsepvll
akgscaysdlqsmgtgpdgsplfgclyeandyeeivflmftlkqafpaey

SCOPe Domain Coordinates for d4ncsa_:

Click to download the PDB-style file with coordinates for d4ncsa_.
(The format of our PDB-style files is described here.)

Timeline for d4ncsa_: