Lineage for d4ncsa1 (4ncs A:4-377)

  1. Root: SCOPe 2.07
  2. 2344607Class b: All beta proteins [48724] (178 folds)
  3. 2398193Fold b.68: 6-bladed beta-propeller [50938] (11 superfamilies)
    consists of six 4-stranded beta-sheet motifs; meander
  4. 2398194Superfamily b.68.1: Sialidases [50939] (3 families) (S)
  5. 2398195Family b.68.1.1: Sialidases (neuraminidases) [50940] (10 protein domains)
  6. 2398492Protein automated matches [193245] (14 species)
    not a true protein
  7. 2398493Species Human (Homo sapiens) [TaxId:9606] [228885] (2 PDB entries)
  8. 2398494Domain d4ncsa1: 4ncs A:4-377 [230156]
    Other proteins in same PDB: d4ncsa2
    automated match to d4nc5a_
    complexed with fsr, po4

Details for d4ncsa1

PDB Entry: 4ncs (more details), 2.2 Å

PDB Description: human sialidase 2 in complex with 2,3-difluorosialic acid (covalent intermediate)
PDB Compounds: (A:) Sialidase-2

SCOPe Domain Sequences for d4ncsa1:

Sequence, based on SEQRES records: (download)

>d4ncsa1 b.68.1.1 (A:4-377) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lpvlqkesvfqsgahayripallylpgqqsllafaeqraskkaehaelivlrrgdydapt
hqvqwqaqevvaqarldghrsmnpcplydaqtgtlflffiaipgqvteqqqlqtranvtr
lcqvtstdhgrtwssprdltdaaigpayrewstfavgpghclqlndrarslvvpayayrk
lhpiqrpipsafcflshdhgrtwarghfvaqdtlecqvaevetgeqrvvtlnarshlrar
vqaqstndgldfqesqlvkklvepppqgcqgsvisfpsprsgpgspaqwllythpthswq
radlgaylnprppapeawsepvllakgscaysdlqsmgtgpdgsplfgclyeandyeeiv
flmftlkqafpaey

Sequence, based on observed residues (ATOM records): (download)

>d4ncsa1 b.68.1.1 (A:4-377) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lpvlqkesvfqsgahayripallylpgqqsllafaeqraaelivlrrgdydapthqvqwq
aqevvaqarldghrsmnpcplydaqtgtlflffiaipganvtrlcqvtstdhgrtwsspr
dltdaaigpayrewstfavgpghclqlndrarslvvpayayrklhpiqrpipsafcflsh
dhgrtwarghfvaqdtlecqvaeveqrvvtlnarshlrarvqaqstndgldfqesqlvkk
lvepppqgcqgsvisfpspraqwllythpthswqradlgaylnprppapeawsepvllak
gscaysdlqsmgtgpdgsplfgclyeandyeeivflmftlkqafpaey

SCOPe Domain Coordinates for d4ncsa1:

Click to download the PDB-style file with coordinates for d4ncsa1.
(The format of our PDB-style files is described here.)

Timeline for d4ncsa1:

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Domains from same chain:
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d4ncsa2