SCOPe 2.03: Domain d4fraa_: 4fra A:

Lineage for d4fraa_ (4fra A:)

1. Root: SCOPe 2.03

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.68: Nucleotide-diphospho-sugar transferases [53447] (1 superfamily)
   3 layers: a/b/a; mixed beta-sheet of 7 strands, order 3214657; strand 6 is antiparallel to the rest

4. Superfamily c.68.1: Nucleotide-diphospho-sugar transferases [53448] (20 families)

5. Family c.68.1.9: alpha-1,3-galactosyltransferase-like [64131] (4 proteins)
   automatically mapped to Pfam PF03414

6. Protein Glycosyltransferase A catalytic domain [75276] (1 species)
   involved in blood group antigen biosynthesis

7. Species Human (Homo sapiens) [TaxId:9606] [75277] (52 PDB entries)
   Uniprot P16442 64-345

8. Domain d4fraa_: 4fra A: [230005]
   automated match to d3sxaa_
   complexed with gal, peg, udp

Details for d4fraa_

PDB Entry: 4fra, 1.43 Å

PDB Description: crystal structure of abba+udp+gal at ph 5.0 with mpd as the cryoprotectant

PDB Compounds: (A:) Histo-blood group ABO system transferase

SCOPe Domain Sequences for d4fraa_:

Sequence, based on SEQRES records:

>d4fraa_ c.68.1.9 (A:) Glycosyltransferase A catalytic domain {Human (Homo sapiens) [TaxId: 9606]}
fmvslprmvypqpkvltpcrkdvlvvtpwlapivwegtfnidilneqfrlqnttigltvf
aikkyvaflklfletaekhfmvghrvhyyvftdqpaavprvtlgtgrqlsvlevraykrw
qdvsmrrmemisdfcerrflsevdylvcvdvdmefrdhvgveiltplfgtlhpsfygssr
eaftyerrpqsqayipkdegdfyymggffggsvqevqrltrachqammvdqangieavwh
deshlnkyllrhkptkvlspeylwdqqllgwpavlrklrftavp

Sequence, based on observed residues (ATOM records):

>d4fraa_ c.68.1.9 (A:) Glycosyltransferase A catalytic domain {Human (Homo sapiens) [TaxId: 9606]}
fmvslprmvypqpkvltpcrkdvlvvtpwlapivwegtfnidilneqfrlqnttigltvf
aikkyvaflklfletaekhfmvghrvhyyvftdqpaavprvtlgtgrqlsvlevrrrmem
iscerrflsevdylvcvdvdmefrdhvgveiltplfgtlhpsfygssreaftyerrpqsq
ayipkdegdfyymggffggsvqevqrltrachqammvdqangieavwhdeshlnkyllrh
kptkvlspeylwdqqllgwpavlrklrftavp

Timeline for d4fraa_:

• d4fraa_ is new in SCOPe 2.03-stable
  
• d4fraa_ appears in SCOPe 2.04
  
• d4fraa_ appears in the current release, SCOPe 2.08, called d4fraa1