SCOPe 2.04: Domain d4nk9b_: 4nk9 B:

Lineage for d4nk9b_ (4nk9 B:)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein Fibroblast growth factor receptor 1 [56158] (1 species)
   PTK group; FGFR subfamily; membrane spanning protein tyrosine kinase

7. Species Human (Homo sapiens) [TaxId:9606] [56159] (20 PDB entries)

8. Domain d4nk9b_: 4nk9 B: [229978]
   automated match to d4f65b_
   complexed with 2k5, edo, so4

Details for d4nk9b_

PDB Entry: 4nk9, 2.57 Å

PDB Description: Crystal structure of human fibroblast growth factor receptor 1 kinase domain in complex with pyrazolaminopyrimidine 1

PDB Compounds: (B:) fibroblast growth factor receptor 1

SCOPe Domain Sequences for d4nk9b_:

Sequence, based on SEQRES records:

>d4nk9b_ d.144.1.7 (B:) Fibroblast growth factor receptor 1 {Human (Homo sapiens) [TaxId: 9606]}
vseyelpedprwelprdrlvlgkplgegafgqvvlaeaigldkdkpnrvtkvavkmlksd
atekdlsdlisememmkmigkhkniinllgactqdgplyviveyaskgnlreylqarrpp
gleysynpshnpeeqlsskdlvscayqvargmeylaskkcihrdlaarnvlvtednvmki
adfglardihhidyykkttngrlpvkwmapealfdriythqsdvwsfgvllweiftlggs
pypgvpveelfkllkeghrmdkpsnctnelymmmrdcwhavpsqrptfkqlvedldriva
ltsnqe

Sequence, based on observed residues (ATOM records):

>d4nk9b_ d.144.1.7 (B:) Fibroblast growth factor receptor 1 {Human (Homo sapiens) [TaxId: 9606]}
vseyelpedprwelprdrlvlgkplgegafgqvvlaeaigldkpnrvtkvavkmlksdat
ekdlsdlisememmkmigkhkniinllgactqdgplyviveyaskgnlreylqarrppql
sskdlvscayqvargmeylaskkcihrdlaarnvlvtednvmkiadfgdyykkttngrlp
vkwmapealfdriythqsdvwsfgvllweiftlggspypgvpveelfkllkeghrmdkps
nctnelymmmrdcwhavpsqrptfkqlvedldrivaltsnqe

Timeline for d4nk9b_:

• d4nk9b_ first appeared in SCOPe 2.03
  
• d4nk9b_ appears in SCOPe 2.05
  
• d4nk9b_ appears in the current release, SCOPe 2.08