SCOPe 2.06: Domain d4nr4a_: 4nr4 A:

Lineage for d4nr4a_ (4nr4 A:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.29: Bromodomain-like [47363] (15 superfamilies)
   4 helices; bundle; minor mirror variant of up-and-down topology

4. Superfamily a.29.2: Bromodomain [47370] (2 families)

5. Family a.29.2.1: Bromodomain [47371] (5 proteins)

6. Protein automated matches [190366] (2 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187201] (61 PDB entries)

8. Domain d4nr4a_: 4nr4 A: [229960]
   automated match to d3p1fa_
   complexed with 2lk, edo, mg

Details for d4nr4a_

PDB Entry: 4nr4, 1.69 Å

PDB Description: crystal structure of the bromodomain of human crebbp in complex with an isoxazolyl-benzimidazole ligand

PDB Compounds: (A:) creb-binding protein

SCOPe Domain Sequences for d4nr4a_:

Sequence; same for both SEQRES and ATOM records:

>d4nr4a_ a.29.2.1 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
fkpeelrqalmptlealyrqdpeslpfrqpvdpqllgipdyfdivknpmdlstikrkldt
gqyqepwqyvddvwlmfnnawlynrktsrvykfcsklaevfeqeidpvmqslg

Timeline for d4nr4a_:

• d4nr4a_ first appeared in SCOPe 2.03
  
• d4nr4a_ appears in SCOPe 2.05
  
• d4nr4a_ appears in SCOPe 2.07
  
• d4nr4a_ appears in the current release, SCOPe 2.08