Lineage for d4cfwd2 (4cfw D:310-432)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 2000824Fold a.74: Cyclin-like [47953] (1 superfamily)
    core: 5 helices; one helix is surrounded by the others
  4. 2000825Superfamily a.74.1: Cyclin-like [47954] (4 families) (S)
    duplication: consists of two domains of this fold
  5. 2000826Family a.74.1.1: Cyclin [47955] (9 protein domains)
  6. 2000839Protein Cyclin A [47956] (2 species)
  7. 2000875Species Human (Homo sapiens) [TaxId:9606] [47957] (78 PDB entries)
    Uniprot P20248 175-432
  8. 2001101Domain d4cfwd2: 4cfw D:310-432 [229795]
    Other proteins in same PDB: d4cfwa1, d4cfwa2, d4cfwc1, d4cfwc2
    automated match to d1h1pb2
    complexed with sq9

Details for d4cfwd2

PDB Entry: 4cfw (more details), 2.45 Å

PDB Description: Structure-based design of C8-substituted O6-cyclohexylmethoxyguanine CDK1 and 2 inhibitors.
PDB Compounds: (D:) Cyclin-A2

SCOPe Domain Sequences for d4cfwd2:

Sequence; same for both SEQRES and ATOM records: (download)

>d4cfwd2 a.74.1.1 (D:310-432) Cyclin A {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d4cfwd2:

Click to download the PDB-style file with coordinates for d4cfwd2.
(The format of our PDB-style files is described here.)

Timeline for d4cfwd2: