SCOPe 2.05: Domain d4ixua_: 4ixu A:

Lineage for d4ixua_ (4ixu A:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.42: Arginase/deacetylase [52767] (1 superfamily)
   3 layers: a/b/a, parallel beta-sheet of 8 strands, order 21387456

4. Superfamily c.42.1: Arginase/deacetylase [52768] (3 families)

5. Family c.42.1.1: Arginase-like amidino hydrolases [52769] (5 proteins)
   Pfam PF00491

6. Protein Arginase [52770] (5 species)

7. Species Human (Homo sapiens), isoform II, mitochondrial [TaxId:9606] [102412] (7 PDB entries)

8. Domain d4ixua_: 4ixu A: [229622]
   automated match to d1pq3a_
   complexed with 38i, ben, bme, mn

Details for d4ixua_

PDB Entry: 4ixu, 1.9 Å

PDB Description: Crystal structure of human Arginase-2 complexed with inhibitor 11d: {(5R)-5-amino-5-carboxy-5-[(3-endo)-8-(3,4-dichlorobenzyl)-8-azabicyclo[3.2.1]oct-3-yl]pentyl}(trihydroxy)borate(1-)

PDB Compounds: (A:) Arginase-2, mitochondrial

SCOPe Domain Sequences for d4ixua_:

Sequence; same for both SEQRES and ATOM records:

>d4ixua_ c.42.1.1 (A:) Arginase {Human (Homo sapiens), isoform II, mitochondrial [TaxId: 9606]}
hsvavigapfsqgqkrkgvehgpaaireaglmkrlsslgchlkdfgdlsftpvpkddlyn
nlivnprsvglanqelaevvsravsdgyscvtlggdhslaigtisgharhcpdlcvvwvd
ahadintplttssgnlhgqpvsfllrelqdkvpqlpgfswikpcissasivyiglrdvdp
pehfilknydiqyfsmrdidrlgiqkvmertfdlligkrqrpihlsfdidafdptlapat
gtpvvggltyregmyiaeeihntgllsaldlvevnpqlatseeeakttanlavdviassf
gqtreg

Timeline for d4ixua_:

• d4ixua_ first appeared in SCOPe 2.03
  
• d4ixua_ appears in SCOPe 2.04
  
• d4ixua_ appears in SCOPe 2.06
  
• d4ixua_ appears in the current release, SCOPe 2.08