SCOPe 2.06: Domain d4ixvb_: 4ixv B:

Lineage for d4ixvb_ (4ixv B:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.42: Arginase/deacetylase [52767] (1 superfamily)
   3 layers: a/b/a, parallel beta-sheet of 8 strands, order 21387456

4. Superfamily c.42.1: Arginase/deacetylase [52768] (3 families)

5. Family c.42.1.1: Arginase-like amidino hydrolases [52769] (5 proteins)
   Pfam PF00491

6. Protein Arginase [52770] (5 species)

7. Species Human (Homo sapiens), isoform II, mitochondrial [TaxId:9606] [102412] (7 PDB entries)

8. Domain d4ixvb_: 4ixv B: [229619]
   automated match to d1pq3a_
   complexed with ben, bme, mn, xa1

Details for d4ixvb_

PDB Entry: 4ixv, 2.3 Å

PDB Description: crystal structure of human arginase-2 complexed with inhibitor 2d: {(5r)-5-amino-5-carboxy-5-[1-(4-chlorobenzyl)piperidin-4- yl]pentyl}(trihydroxy)borate(1-)

PDB Compounds: (B:) Arginase-2, mitochondrial

SCOPe Domain Sequences for d4ixvb_:

Sequence; same for both SEQRES and ATOM records:

>d4ixvb_ c.42.1.1 (B:) Arginase {Human (Homo sapiens), isoform II, mitochondrial [TaxId: 9606]}
hsvavigapfsqgqkrkgvehgpaaireaglmkrlsslgchlkdfgdlsftpvpkddlyn
nlivnprsvglanqelaevvsravsdgyscvtlggdhslaigtisgharhcpdlcvvwvd
ahadintplttssgnlhgqpvsfllrelqdkvpqlpgfswikpcissasivyiglrdvdp
pehfilknydiqyfsmrdidrlgiqkvmertfdlligkrqrpihlsfdidafdptlapat
gtpvvggltyregmyiaeeihntgllsaldlvevnpqlatseeeakttanlavdviassf
gqtreg

Timeline for d4ixvb_:

• d4ixvb_ first appeared in SCOPe 2.03
  
• d4ixvb_ appears in SCOPe 2.05
  
• d4ixvb_ appears in SCOPe 2.07
  
• d4ixvb_ appears in the current release, SCOPe 2.08