SCOPe 2.08: Domain d4c2ra_: 4c2r A:

Lineage for d4c2ra_ (4c2r A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.92: Zincin-like [55485] (2 superfamilies)
   contains mixed beta sheet with connection over free side of the sheet

4. Superfamily d.92.1: Metalloproteases ('zincins'), catalytic domain [55486] (18 families)

5. Family d.92.1.5: Neurolysin-like [55505] (5 proteins)
   combines M2, M3 and M32 families of metalloproteases
   the N-terminal half of the structure is multihelical; the C-terminal half contains the thermolysin-like catalytic domain

6. Protein automated matches [190340] (5 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187164] (8 PDB entries)

8. Domain d4c2ra_: 4c2r A: [229517]
   automated match to d3bkka_
   complexed with act, cl, pe4, so4, zn; mutant

Details for d4c2ra_

PDB Entry: 4c2r, 2.3 Å

PDB Description: crystal structure of human testis angiotensin-i converting enzyme mutant r522q

PDB Compounds: (A:) angiotensin-converting enzyme

SCOPe Domain Sequences for d4c2ra_:

Sequence, based on SEQRES records:

>d4c2ra_ d.92.1.5 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
deaeaskfveeydrtsqvvwneyaeanwnyntnittetskillqknmqianhtlkygtqa
rkfdvnqlqnttikriikkvqdleraalpaqeleeynkilldmettysvatvchpngscl
qlepdltnvmatsrkyedllwawegwrdkagrailqfypkyvelinqaarlngyvdagds
wrsmyetpsleqdlerlfqelqplylnlhayvrralhrhygaqhinlegpipahllgnmw
aqtwsniydlvvpfpsapsmdtteamlkqgwtprrmfkeaddfftslgllpvppefwnks
mlekptdgrevvchasawdfyngkdfrikqcttvnledlvvahhemghiqyfmqykdlpv
alreganpgfheaigdvlalsvstpkhlhslnllsseggsdehdinflmkmaldkiafip
fsylvdqwrwrvfdgsitkenynqewwslrlkyqglcppvprtqgdfdpgakfhipssvp
yiqyfvsfiiqfqfhealcqaaghtgplhkcdiyqskeagqrlatamklgfsrpwpeamq
litgqpnmsasamlsyfkplldwlrtenelhgeklgwpqynwtpn

Sequence, based on observed residues (ATOM records):

>d4c2ra_ d.92.1.5 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
deaeaskfveeydrtsqvvwneyaeanwnyntnittetskillqknmqianhtlkygtqa
rkfdvnqlqnttikriikkvqdleraalpaqeleeynkilldmettysvatvchpngscl
qlepdltnvmatsrkyedllwawegwrdkagrailqfypkyvelinqaarlngyvdagds
wrsmyetpsleqdlerlfqelqplylnlhayvrralhrhygaqhinlegpipahllgnmw
aqtwsniydlvvpfpsapsmdtteamlkqgwtprrmfkeaddfftslgllpvppefwnks
mlekptdgrevvchasawdfyngkdfrikqcttvnledlvvahhemghiqyfmqykdlpv
alreganpgfheaigdvlalsvstpkhlhslnllseggsdehdinflmkmaldkiafipf
sylvdqwrwrvfdgsitkenynqewwslrlkyqglcppvprtqgdfdpgakfhipssvpy
iqyfvsfiiqfqfhealcqaaghtgplhkcdiyqskeagqrlatamklgfsrpwpeamql
itgqpnmsasamlsyfkplldwlrtenelhgeklgwpqynwtpn

Timeline for d4c2ra_:

• d4c2ra_ first appeared in SCOPe 2.03
  
• d4c2ra_ appears in SCOPe 2.07