SCOPe 2.08: Domain d4mwia_: 4mwi A:

Lineage for d4mwia_ (4mwi A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (37 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1476 PDB entries)

8. Domain d4mwia_: 4mwi A: [229442]
   automated match to d3og7a_
   complexed with gol, pxn

Details for d4mwia_

PDB Entry: 4mwi, 1.7 Å

PDB Description: Crystal structure of the human MLKL pseudokinase domain

PDB Compounds: (A:) mixed lineage kinase domain-like protein

SCOPe Domain Sequences for d4mwia_:

Sequence, based on SEQRES records:

>d4mwia_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ikeikkeqlsgspwillrenevstlykgeyhrapvaikvfkklqagsiaivrqtfnkeik
tmkkfespnilrifgicidetvtppqfsivmeycelgtlrelldrekdltlgkrmvlvlg
aarglyrlhhseapelhgkirssnflvtqgyqvklagfelrktqtsmslgttrektdrvk
staylspqeledvfyqydvkseiysfgivlweiatgdipfqgcnsekirklvavkrqqep
lgedcpselreiidecrahdpsvrpsvdeilkklstfs

Sequence, based on observed residues (ATOM records):

>d4mwia_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
ikeikkeqlsgspwillrenevstlykgeyhrapvaikvfkklqagsiaivrqtfnkeik
tmkkfespnilrifgicidetvtppqfsivmeycelgtlrelldrekdltlgkrmvlvlg
aarglyrlhhseapelhgkirssnflvtqgyqvklagfelrktqdrvkstaylspqeled
vfyqydvkseiysfgivlweiatgdipfqgcnsekirklvavkrqqeplgedcpselrei
idecrahdpsvrpsvdeilkklstfs

Timeline for d4mwia_:

• d4mwia_ first appeared in SCOPe 2.03
  
• d4mwia_ appears in SCOPe 2.07