SCOPe 2.05: Domain d4cghb_: 4cgh B:

Lineage for d4cghb_ (4cgh B:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest

4. Superfamily c.55.3: Ribonuclease H-like [53098] (15 families)
   consists of one domain of this fold

5. Family c.55.3.2: Retroviral integrase, catalytic domain [53107] (2 proteins)

6. Protein automated matches [190209] (4 species)
   not a true protein

7. Species Human immunodeficiency virus 1 [TaxId:11676] [186963] (61 PDB entries)

8. Domain d4cghb_: 4cgh B: [229392]
   automated match to d4ah9a_
   complexed with acy, loz, so4

Details for d4cghb_

PDB Entry: 4cgh, 1.76 Å

PDB Description: Interrogating HIV integrase for compounds that bind- a SAMPL challenge

PDB Compounds: (B:) integrase

SCOPe Domain Sequences for d4cghb_:

Sequence, based on SEQRES records:

>d4cghb_ c.55.3.2 (B:) automated matches {Human immunodeficiency virus 1 [TaxId: 11676]}
spgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvhtd
ngsnftsttvkaacwwagikqedgipynpqsqgviesmnkelkkiigqvrdqaehlktav
qmavfihnhkrkggiggysagerivdiiatdiq

Sequence, based on observed residues (ATOM records):

>d4cghb_ c.55.3.2 (B:) automated matches {Human immunodeficiency virus 1 [TaxId: 11676]}
spgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktvhtd
ngsnftsttvkaacwwagikqedgipynpqsqgviesmnkelkkiigqvrdqaehlktav
qmavfihnhkrkgysagerivdiiatdiq

Timeline for d4cghb_:

• d4cghb_ first appeared in SCOPe 2.03
  
• d4cghb_ appears in SCOPe 2.04
  
• d4cghb_ appears in SCOPe 2.06
  
• d4cghb_ appears in the current release, SCOPe 2.08