Lineage for d3zcla_ (3zcl A:)

  1. Root: SCOPe 2.05
  2. 1886641Class d: Alpha and beta proteins (a+b) [53931] (381 folds)
  3. 1929110Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1929111Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1929232Family d.144.1.7: Protein kinases, catalytic subunit [88854] (64 proteins)
    members organized in the groups and subfamiles specified by the comments
  6. 1931583Protein automated matches [190091] (12 species)
    not a true protein
  7. 1931656Species Human (Homo sapiens) [TaxId:9606] [188447] (553 PDB entries)
  8. 1931677Domain d3zcla_: 3zcl A: [229379]
    automated match to d4ap7a_
    complexed with 5tf

Details for d3zcla_

PDB Entry: 3zcl (more details), 1.4 Å

PDB Description: x-ray structure of c-met kinase in complex with inhibitor (s)-3-(1- (1h-pyrrolo(2,3-b)pyridin-3-yl)ethyl)-n-isopropyl-(1,2,4)triazolo(4, 3- b)pyridazin-6-amine
PDB Compounds: (A:) Hepatocyte growth factor receptor

SCOPe Domain Sequences for d3zcla_:

Sequence, based on SEQRES records: (download)

>d3zcla_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
hidlsalnpelvqavqhvvigpsslivhfnevigrghfgcvyhgtlldndgkkihcavks
lnritdigevsqfltegiimkdfshpnvlsllgiclrsegsplvvlpymkhgdlrnfirn
ethnptvkdligfglqvakgmkylaskkfvhrdlaarncmldekftvkvadfglardmyd
keyysvhnktgaklpvkwmaleslqtqkfttksdvwsfgvllwelmtrgappypdvntfd
itvyllqgrrllqpeycpdplyevmlkcwhpkaemrpsfselvsrisaifstfi

Sequence, based on observed residues (ATOM records): (download)

>d3zcla_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
hidlsalnpelvqavqhvvigpsslivhfnevigrghfgcvyhgtlldkkihcavkslnr
itdigevsqfltegiimkdfshpnvlsllgiclrsegsplvvlpymkhgdlrnfirneth
nptvkdligfglqvakgmkylaskkfvhrdlaarncmldekftvkvadfglardmydkey
ysvhnktgaklpvkwmaleslqtqkfttksdvwsfgvllwelmtrgappypdvntfditv
yllqgrrllqpeycpdplyevmlkcwhpkaemrpsfselvsrisaifstfi

SCOPe Domain Coordinates for d3zcla_:

Click to download the PDB-style file with coordinates for d3zcla_.
(The format of our PDB-style files is described here.)

Timeline for d3zcla_: