SCOPe 2.03: Domain d4mr4a_: 4mr4 A:

Lineage for d4mr4a_ (4mr4 A:)

1. Root: SCOPe 2.03

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.29: Bromodomain-like [47363] (15 superfamilies)
   4 helices; bundle; minor mirror variant of up-and-down topology

4. Superfamily a.29.2: Bromodomain [47370] (2 families)

5. Family a.29.2.0: automated matches [191428] (1 protein)
   not a true family

6. Protein automated matches [190615] (4 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187641] (145 PDB entries)

8. Domain d4mr4a_: 4mr4 A: [229331]
   automated match to d3p5oa_
   complexed with 1k0, edo

Details for d4mr4a_

PDB Entry: 4mr4, 1.66 Å

PDB Description: Crystal Structure of the first bromodomain of human BRD4 in complex with a quinazolinone ligand (RVX-208)

PDB Compounds: (A:) Bromodomain-containing protein 4

SCOPe Domain Sequences for d4mr4a_:

Sequence; same for both SEQRES and ATOM records:

>d4mr4a_ a.29.2.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
nelptee

Timeline for d4mr4a_:

• d4mr4a_ is new in SCOPe 2.03-stable
  
• d4mr4a_ appears in SCOPe 2.04
  
• d4mr4a_ appears in the current release, SCOPe 2.08, called d4mr4a1