SCOPe 2.08: Domain d4l8ga_: 4l8g A:

Lineage for d4l8ga_ (4l8g A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (27 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.8: G proteins [52592] (81 proteins)
   core: mixed beta-sheet of 6 strands, order 231456; strand 2 is antiparallel to the rest

6. Protein automated matches [190047] (37 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [186768] (291 PDB entries)

8. Domain d4l8ga_: 4l8g A: [229307]
   automated match to d4epxa_
   complexed with gdp, mg, na

Details for d4l8ga_

PDB Entry: 4l8g, 1.52 Å

PDB Description: crystal structure of k-ras g12c, gdp-bound

PDB Compounds: (A:) GTPase KRas

SCOPe Domain Sequences for d4l8ga_:

Sequence, based on SEQRES records:

>d4l8ga_ c.37.1.8 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mteyklvvvgacgvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildtag
qeeysamrdqymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgnkcdl
psrtvdtkqaqdlarsygipfietsaktrqgvddafytlvreirkhk

Sequence, based on observed residues (ATOM records):

>d4l8ga_ c.37.1.8 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
mteyklvvvgacgvgksaltiqliqnhfvdeydptiedsyrkqvvidgetclldildtaq
ymrtgegflcvfainntksfedihhyreqikrvkdsedvpmvlvgnkcdlpsrtvdtkqa
qdlarsygipfietsaktrqgvddafytlvreirkhk

Timeline for d4l8ga_:

• d4l8ga_ first appeared in SCOPe 2.03
  
• d4l8ga_ appears in SCOPe 2.07