SCOPe 2.07: Domain d4meqa1: 4meq A:44-168

Lineage for d4meqa1 (4meq A:44-168)

1. Root: SCOPe 2.07

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.29: Bromodomain-like [47363] (15 superfamilies)
   4 helices; bundle; minor mirror variant of up-and-down topology

4. Superfamily a.29.2: Bromodomain [47370] (2 families)

5. Family a.29.2.0: automated matches [191428] (1 protein)
   not a true family

6. Protein automated matches [190615] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187641] (1004 PDB entries)

8. Domain d4meqa1: 4meq A:44-168 [228715]
   Other proteins in same PDB: d4meqa2
   automated match to d3p5oa_
   complexed with 25o, edo

Details for d4meqa1

PDB Entry: 4meq, 1.77 Å

PDB Description: Crystal Structure of the first bromodomain of human BRD4 in complex with a 5-methyl-triazolopyrimidine ligand

PDB Compounds: (A:) Bromodomain-containing protein 4

SCOPe Domain Sequences for d4meqa1:

Sequence; same for both SEQRES and ATOM records:

>d4meqa1 a.29.2.0 (A:44-168) automated matches {Human (Homo sapiens) [TaxId: 9606]}
nppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykiikt
pmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqkine
lptee

Timeline for d4meqa1:

• d4meqa1 first appeared in SCOPe 2.03, called d4meqa_
  
• d4meqa1 appears in SCOPe 2.06
  
• d4meqa1 appears in the current release, SCOPe 2.08