SCOPe 2.04: Domain d4meqa_: 4meq A:

Lineage for d4meqa_ (4meq A:)

1. Root: SCOPe 2.04

2. Class a: All alpha proteins [46456] (285 folds)

3. Fold a.29: Bromodomain-like [47363] (15 superfamilies)
   4 helices; bundle; minor mirror variant of up-and-down topology

4. Superfamily a.29.2: Bromodomain [47370] (2 families)

5. Family a.29.2.0: automated matches [191428] (1 protein)
   not a true family

6. Protein automated matches [190615] (4 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187641] (182 PDB entries)

8. Domain d4meqa_: 4meq A: [228715]
   automated match to d3p5oa_
   complexed with 25o, edo

Details for d4meqa_

PDB Entry: 4meq, 1.77 Å

PDB Description: Crystal Structure of the first bromodomain of human BRD4 in complex with a 5-methyl-triazolopyrimidine ligand

PDB Compounds: (A:) Bromodomain-containing protein 4

SCOPe Domain Sequences for d4meqa_:

Sequence; same for both SEQRES and ATOM records:

>d4meqa_ a.29.2.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
nelptee

Timeline for d4meqa_:

• d4meqa_ first appeared in SCOPe 2.03
  
• d4meqa_ appears in SCOPe 2.05
  
• d4meqa_ appears in the current release, SCOPe 2.08, called d4meqa1