Lineage for d4h25d1 (4h25 D:3-81)

  1. Root: SCOPe 2.05
  2. 1886641Class d: Alpha and beta proteins (a+b) [53931] (381 folds)
  3. 1897191Fold d.19: MHC antigen-recognition domain [54451] (1 superfamily)
    dimeric
  4. 1897192Superfamily d.19.1: MHC antigen-recognition domain [54452] (2 families) (S)
  5. 1897193Family d.19.1.1: MHC antigen-recognition domain [54453] (13 proteins)
  6. 1897796Protein Class II MHC alpha chain, N-terminal domain [88806] (15 species)
  7. 1897806Species Human (Homo sapiens), HLA-DR1 [TaxId:9606] [88808] (18 PDB entries)
    Uniprot P01903 28-207
  8. 1897809Domain d4h25d1: 4h25 D:3-81 [228336]
    Other proteins in same PDB: d4h25a2, d4h25b1, d4h25b2, d4h25d2, d4h25e1, d4h25e2
    automated match to d1kg0a2
    complexed with ipa

Details for d4h25d1

PDB Entry: 4h25 (more details), 2.2 Å

PDB Description: TCR interaction with peptide mimics of nickel offers structure insights to nickel contact allergy
PDB Compounds: (D:) hla class II histocompatibility antigen, dr alpha chain

SCOPe Domain Sequences for d4h25d1:

Sequence; same for both SEQRES and ATOM records: (download)

>d4h25d1 d.19.1.1 (D:3-81) Class II MHC alpha chain, N-terminal domain {Human (Homo sapiens), HLA-DR1 [TaxId: 9606]}
eehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgalan
iavdkanleimtkrsnytp

SCOPe Domain Coordinates for d4h25d1:

Click to download the PDB-style file with coordinates for d4h25d1.
(The format of our PDB-style files is described here.)

Timeline for d4h25d1: