Lineage for d4kbnb_ (4kbn B:)

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2477518Fold c.71: Dihydrofolate reductase-like [53596] (1 superfamily)
    3 layers: a/b/a; mixed beta-sheet of 8 strands, order 34251687; strand 8 is antiparallel to the rest
  4. 2477519Superfamily c.71.1: Dihydrofolate reductase-like [53597] (3 families) (S)
  5. 2477520Family c.71.1.1: Dihydrofolate reductases [53598] (4 protein domains)
  6. 2477723Protein Dihydrofolate reductases, eukaryotic type [53605] (7 species)
  7. 2477771Species Human (Homo sapiens) [TaxId:9606] [53607] (73 PDB entries)
  8. 2477832Domain d4kbnb_: 4kbn B: [228208]
    automated match to d1kmva_
    complexed with 25u, cl, eoh, mg, ndp, nh4, sr

Details for d4kbnb_

PDB Entry: 4kbn (more details), 1.84 Å

PDB Description: human dihydrofolate reductase complexed with NADPH and 5-{3-[3-(3,5-pyrimidine)]-phenyl-prop-1-yn-1-yl}-6-ethyl-pyrimidine-2,4diamine
PDB Compounds: (B:) dihydrofolate reductase

SCOPe Domain Sequences for d4kbnb_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4kbnb_ c.71.1.1 (B:) Dihydrofolate reductases, eukaryotic type {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d4kbnb_:

Click to download the PDB-style file with coordinates for d4kbnb_.
(The format of our PDB-style files is described here.)

Timeline for d4kbnb_: