Lineage for d4lc7a1 (4lc7 A:58-453)

  1. Root: SCOPe 2.06
  2. 2017114Class b: All beta proteins [48724] (177 folds)
  3. 2058814Fold b.50: Acid proteases [50629] (1 superfamily)
    barrel, closed; n=6, S=10, complex topology
  4. 2058815Superfamily b.50.1: Acid proteases [50630] (4 families) (S)
  5. 2060177Family b.50.1.2: Pepsin-like [50646] (11 protein domains)
    duplication: consists of two similar barrel domains
    N-terminal: barrel, partly opened; n*=6, S*=10
  6. 2060235Protein beta-secretase (memapsin) [50671] (1 species)
  7. 2060236Species Human (Homo sapiens) [TaxId:9606] [50672] (275 PDB entries)
    Uniprot P56817 58-446 ! Uniprot P56817 60-447
  8. 2060278Domain d4lc7a1: 4lc7 A:58-453 [227976]
    Other proteins in same PDB: d4lc7a2
    automated match to d4hzta_
    complexed with 1wp, ni

Details for d4lc7a1

PDB Entry: 4lc7 (more details), 1.7 Å

PDB Description: Aminooxazoline inhibitor of BACE-1
PDB Compounds: (A:) Beta-Secretase-1

SCOPe Domain Sequences for d4lc7a1:

Sequence; same for both SEQRES and ATOM records: (download)

>d4lc7a1 b.50.1.2 (A:58-453) beta-secretase (memapsin) {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d4lc7a1:

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Timeline for d4lc7a1:

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Domains from same chain:
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