SCOPe 2.03: Domain d4bw3a_: 4bw3 A:

Lineage for d4bw3a_ (4bw3 A:)

1. Root: SCOPe 2.03

2. Class a: All alpha proteins [46456] (284 folds)

3. Fold a.29: Bromodomain-like [47363] (15 superfamilies)
   4 helices; bundle; minor mirror variant of up-and-down topology

4. Superfamily a.29.2: Bromodomain [47370] (2 families)

5. Family a.29.2.0: automated matches [191428] (1 protein)
   not a true family

6. Protein automated matches [190615] (4 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187641] (145 PDB entries)

8. Domain d4bw3a_: 4bw3 A: [227835]
   automated match to d3p5oa_
   complexed with 9bm, edo

Details for d4bw3a_

PDB Entry: 4bw3, 1.5 Å

PDB Description: The first bromodomain of human BRD4 in complex with 3,5 dimethylisoxaxole ligand

PDB Compounds: (A:) Bromodomain-containing protein 4

SCOPe Domain Sequences for d4bw3a_:

Sequence; same for both SEQRES and ATOM records:

>d4bw3a_ a.29.2.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
smnppppetsnpnkpkrqtnqlqyllrvvlktlwkhqfawpfqqpvdavklnlpdyykii
ktpmdmgtikkrlennyywnaqeciqdfntmftncyiynkpgddivlmaealeklflqki
nelptee

Timeline for d4bw3a_:

• d4bw3a_ is new in SCOPe 2.03-stable
  
• d4bw3a_ appears in SCOPe 2.04
  
• d4bw3a_ appears in the current release, SCOPe 2.08, called d4bw3a1