SCOPe 2.03: Domain d4lrsa1: 4lrs A:10-294

Lineage for d4lrsa1 (4lrs A:10-294)

1. Root: SCOPe 2.03

2. Class c: Alpha and beta proteins (a/b) [51349] (147 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.10: Aldolase [51569] (9 families)
   Common fold covers whole protein structure

5. Family c.1.10.0: automated matches [191319] (1 protein)
   not a true family

6. Protein automated matches [190115] (51 species)
   not a true protein

7. Species Thermomonospora curvata [TaxId:471852] [227770] (2 PDB entries)

8. Domain d4lrsa1: 4lrs A:10-294 [227771]
   Other proteins in same PDB: d4lrsa2
   automated match to d4jn6a1
   complexed with cl, for, gol, mg, nad, peg, pyr, so4

Details for d4lrsa1

PDB Entry: 4lrs, 1.55 Å

PDB Description: Crystal and solution structures of the bifunctional enzyme (Aldolase/Aldehyde dehydrogenase) from Thermomonospora curvata, reveal a cofactor-binding domain motion during NAD+ and CoA accommodation whithin the shared cofactor-binding site

PDB Compounds: (A:) 4-hydroxy-2-oxovalerate aldolase

SCOPe Domain Sequences for d4lrsa1:

Sequence; same for both SEQRES and ATOM records:

>d4lrsa1 c.1.10.0 (A:10-294) automated matches {Thermomonospora curvata [TaxId: 471852]}
aprvritdstlrdgshamahqfteeqvratvhaldaagvevievshgdglggssfnygfs
avdeidlvaaavdeavnakiavlllpgvgtvrdlkrahdagasvariathcteadvscqh
faaarelgmetvgflmlahrigpeelarqarimvdagaqcvyvvdsagalvlsdvqarvq
alvreigheaqvgfhghqnlslgvansvlayqngarqidgalcalgagagnspteilaat
ferlnietgvnvqaalaaaeevvrpylprlpwadraaivqgyagv

Timeline for d4lrsa1:

• d4lrsa1 is new in SCOPe 2.03-stable
  
• d4lrsa1 appears in SCOPe 2.04
  
• d4lrsa1 appears in the current release, SCOPe 2.08